Intra Abdominal Infection and Sepsis

Question 1

define colonisation

Answer 1

bug is there but no inflammatory response

Question 2

define infection

Answer 2

inflammation due to microbe

Question 3

define bacteraemia

Answer 3

viable bacteria in blood

Question 4

timeline thing

Answer 4

colonisation
infection 
SIRS
sepsis
severe sepsis
septic shock

Question 5

define sepsis

Answer 5

a group of symptoms due to life threatening organ dysfunction caused by a dysregulated host response to infection

Question 6

SIRS criteria

Answer 6

temp >38 or <36
HR >90
RR>20
WBC >12000

Question 7

what can SIRS be caused by

Answer 7

trauma
burns
pancreatitis
etc

Question 8

define severe sepsis

Answer 8

sepsis with signs of at least one acute organ dysfunction

Question 9

define septic shock

Answer 9

sever sepsis with hypotension refractory to adequate volume resuscitation

Question 10

CF - local

Answer 10

pain, tenderness, guarding, may PR blood

Question 11

CF - systemic

Answer 11

fever, chills, rigor, nausea and vomiting, diarrhoea or constipation, malaise, anorexia

Question 12

list some gut gram negative commensal coliform

Answer 12

E coli
Klebsiella
Proteus

Question 13

what do we treat gram negative commensal coliforms with

Answer 13

gentamicin

Question 14

list some strict anaerobes

Answer 14

bacteriocides (gram negative) and clostridium (gram positive)

Question 15

what do we treat strict anaerobes with

Answer 15

metronidazole

Question 16

list some aerobic gram positives

Answer 16

streptococci and enterococci

Question 17

what do we treat aerobic gram positive with

Answer 17

amoxicillin

co-trimoxazole if allergic

Question 18

sepsis 6 bundle

Answer 18

take blood 
monitor hourly urine output
give fluids 
give IV antibiotics
 measure lactate and FBC
high flow O2

Question 19

what fluid resuscitation would you give (sepsis 6)

Answer 19

500ml saline immediately

Question 20

what does lactate measure

Answer 20

tissue death

Question 21

what is urine output a measure of

Answer 21

kidney perfusion

Question 22

complication

Answer 22

abscesses

Question 23

treat large abscess

Answer 23

drain

Question 24

why not give large abscesses antibiotics

Answer 24

poor blood supply so poor antibiotics penetration

Question 25

small abscess treatment

Answer 25

antibiotics

Question 26

prophylactic antibiotics for GI surgery

Answer 26

gentamicin and metronidazole