stomach and duodenum Flashcards
gastritis
inflammation causing mucosal injury to stomach
acute gastritis
acidic damage to the stomach due to imbalance between mucosal defence and acidic environment
acute gastritis RF
severe burn, NSAID, heavy alcohol consumption, chemotherapy, increased intracranial pressure
how does inc intracranial pressure cause gastritis
inc stimulation of CNX leads to inc acid production
symptoms of acute gastritis
epigastric pain, bloating, fullness, heartburn, tenderness
what are the ALARM symptoms
Anaemia Loss of weight Anorexia Recent onset/progressive, Malaena/haematemesis, Swallowing difficulty
what is chronic gastritis divided into
H . pylori chronic autoimmune
chronic gastritis is due to what
H pylori induced acute and chronic inflammation
where is the most common site for H.pylori gastritis
antrum
what is the most accurate and non invasive test for H pylori
C urea breath test
if presenting with gastritis and < 55 what do we do
test for H pylori - C urea breath test or stool antigen
if presenting with gastritis and >55
upper GI endoscopy
if H pylori treatment doesnt work
- make sure H pylori has gone - C urea breath test
- stop PPI for 2 weeks and do upper GI endoscopy to exclude cancer
what is the treatment for h pylori
triple OAC or OMC
autoimmune gastritis
antibodies destroy parietal cells and IF deficiency leading to gastric atrophy
where is autoimmune gastritis located
fundus and body
what can autoimmune gastritis lead to
pernicious anaemia and metaplasia
what is there a risk of with autoimmune gastritis
malignancy
what is Gastroparesis
delayed gastric emptying that isnt due to obstruction
Gastroparesis CF
feeling of fullness and bloating
abdominal pain
weight loss
nausea and vomiting
Gastroparesis investigation
oesophageal manometry
Gastroparesis treatment
removal of precipitating factor
liquid diet and nutritional support
gastric pacemaker
