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RB Y1 GI > tropical sprue, SBO and whipple's > Flashcards

tropical sprue, SBO and whipple's Flashcards

1
Q

tropical sprue

A

flattened villi (atrophy) leads to malabsorption

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2
Q

where does tropical sprue effect people

A

tropical regions of world e.g. Caribbean, SE Asia and India, Central and South America

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3
Q

tropical sprue CF

A

diarrhoea, steatorrhoea

dehydration, weight loss, cause, anorexia, anaemia

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4
Q

tropical sprue pattern

A

chronic disease with exacerbations

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5
Q

tropical sprue histology

A

thickened small bowel folds seen on barium swallow is typical

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6
Q

tropical sprue complications

A

megaloblastic anaemia

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7
Q

tropical sprue causes low what levels

A

folate and B12

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8
Q

tropical sprue diagnosis

A

biopsy of jejunum

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9
Q

tropical sprue treatment

A

tetracycline and folate

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10
Q

whipple’s epidemiology

A

white middle aged men in europe

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11
Q

whipple’s causative organism

A

Tropheryma whipplei

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12
Q

does whipple’s cause multi-system involvement

A

yes

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13
Q

whipple’s CF - at first

A

often starts insidiously with arthralgia

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14
Q

whipple’s CF - GI

A

weight loss, diarrhoea, steatorrhoea, abdominal dimension, colicky abdominal pain

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15
Q

whipple’s CF - systemic

A

fever, chronic cough, sweat, lymphadenopathy

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16
Q

whipple’s diagnosis

A

show T whipplei in tissue by microscopy

17
Q

whipple’s treatment

A

antimicrobial

18
Q

SBO CF

A

diarrhoea, steatorrhoea, abode pain, vitamin deficiency

19
Q

what can occur in SBO

A

macrocytic anaemia

20
Q

microcytic anaemia in SBBO is due to

A

B12 deficiency

21
Q

what is macrocytosis also caused by

A

pernicious anaemia

22
Q

what autoimmune phenomenon is associated with pernicious anaemia

A

white hair

23
Q

SBO E/O

A

diverticula, fistula, strictures related to Crohns

post op blind loops

24
Q

SBO lab

A

low cobalamin and high folate
jejunal aspirate
schilling test

25
Q

SBO treatment

A

surgical correction, tetracycline for 2-3 weeks

26
Q

what is the schilling test used for

A

patients with B12 deficiency

to determine if they have pernicious anaemia

27
Q

SBO bacteria

A

usually E.coli and Bacteroides

RB Y1 GI (54 decks)

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