tropical sprue, SBO and whipple's Flashcards
tropical sprue
flattened villi (atrophy) leads to malabsorption
where does tropical sprue effect people
tropical regions of world e.g. Caribbean, SE Asia and India, Central and South America
tropical sprue CF
diarrhoea, steatorrhoea
dehydration, weight loss, cause, anorexia, anaemia
tropical sprue pattern
chronic disease with exacerbations
tropical sprue histology
thickened small bowel folds seen on barium swallow is typical
tropical sprue complications
megaloblastic anaemia
tropical sprue causes low what levels
folate and B12
tropical sprue diagnosis
biopsy of jejunum
tropical sprue treatment
tetracycline and folate
whipple’s epidemiology
white middle aged men in europe
whipple’s causative organism
Tropheryma whipplei
does whipple’s cause multi-system involvement
yes
whipple’s CF - at first
often starts insidiously with arthralgia
whipple’s CF - GI
weight loss, diarrhoea, steatorrhoea, abdominal dimension, colicky abdominal pain
whipple’s CF - systemic
fever, chronic cough, sweat, lymphadenopathy
whipple’s diagnosis
show T whipplei in tissue by microscopy
whipple’s treatment
antimicrobial
SBO CF
diarrhoea, steatorrhoea, abode pain, vitamin deficiency
what can occur in SBO
macrocytic anaemia
microcytic anaemia in SBBO is due to
B12 deficiency
what is macrocytosis also caused by
pernicious anaemia
what autoimmune phenomenon is associated with pernicious anaemia
white hair
SBO E/O
diverticula, fistula, strictures related to Crohns
post op blind loops
SBO lab
low cobalamin and high folate
jejunal aspirate
schilling test
SBO treatment
surgical correction, tetracycline for 2-3 weeks
what is the schilling test used for
patients with B12 deficiency
to determine if they have pernicious anaemia
SBO bacteria
usually E.coli and Bacteroides
