GORD Flashcards
1
Q
GORD
A
reflex of stomach acid causing troublesome symptoms
2
Q
histology
A
basal zone hyperplasia and elongation papillae as cell type changes to deal with acid
3
Q
aetiology
A
defective LOS impaired oesophageal clearance or motility defective mucosal barrier hiatus hernia pregnancy, obesity large fatty meals Ca blockers and nitrates
4
Q
symptoms
A
heartburn - aggregated by lying down
nocturnal cough
water brash
regurgitation of food and acid
5
Q
complications
A
ulceration and bleeding
structure formation due to scarring
oesophageal cancer
barrett
6
Q
investigations
A
endoscopy
Ba swallow
manometry/pH when endoscopy is normal
nuclear imaging rarely
7
Q
treatment
A
lifestyle changes
H2 antagonist
PPI
antacid for symptoms
8
Q
H2 example
A
ranitidine
9
Q
surgery
A
nissen fundoplication
