LFTs

Question 1

what sort of time frame does albumin give

Answer 1

long

Question 2

what sort of time frame does prothrombin give

Answer 2

quick - short half life

Question 3

what is PT a measure of

Answer 3

clotting cascade

Question 4

where is ALT found

Answer 4

specific to liver

Question 5

where is AST found

Answer 5

heart, skeletal muscle, RBC and liver

Question 6

ALT>1000

Answer 6

viral or ischaemic hepatitis

Question 7

what is the AST:ALT ratio like in NAFLD

Answer 7

less than 1: 1

Question 8

what dos 2:1 ratio indicate

Answer 8

alcoholic liver disease

Question 9

what does ALT>AST in hep mean

Answer 9

viral

Question 10

what does AST>ALT in hep mean

Answer 10

alcohol (ALT around 200)

Question 11

reasons for ALP elevation

Answer 11

found in bone and liver and elevated when tissues more metabolically activated eg bone growth in teenagers and pregnancy

Question 12

conditions with raised ALP and GGT

Answer 12

gallstones, PBC, PSC, obstructing tumours

Question 13

reasons for GGT elevation

Answer 13

alcohol, pancreatic disease, COPD, renal failure, diabetes and post-MI.