Thyroid Disorders

Question 1

What is T3 name

Answer 1

triiodothyronine

Question 2

what is T4 name

Answer 2

Thyroxine

Question 3

What stimulates the production of thyroid hormone

Answer 3

the pituitary gland release TSH which stimulates the thyroid

Question 4

which form of thyroid is unbound and active

Answer 4

T4

Question 5

Define Hasimoto’s disease

Answer 5

autoimmune condition in which a patient’s own antibodies attack the thyroid gland causing hypothyroidism

Question 6

Define myxedema coma

Answer 6

potentially fatal complication of hypothyroidism that can occur when hypothyroidism is left untreated for a long time

Question 7

S/Sx of hypothyroidism

Answer 7

cold intolerance
dry skin
fatigue
weight gain
goiter

Question 8

Key drugs that can cause hypothyroidism

Answer 8

"I TALC"
interferons
tyrosine kinase inhibitors
amiodarone
lithium
carbamazepine

Question 9

DOC for hypothyroidism

Answer 9

Levothyroxine (T4)

Question 10

treatment for hypothyroidism

Answer 10

levothyroxine (T4)
liothyronine (T3)
desiccated thyroid (T3&4)

Question 11

levothyroxine dose

Answer 11

1.6 mcg/kg/day

Question 12

Define grave’s disease

Answer 12

common cause of hyperthyroidism

autoimmune disorder that the antibodies stimulate the thyroid to produce too much T4

Question 13

Drugs that cause hyperthyroidism

Answer 13

iodine
amiodarone
interferons

Question 14

S/Sx of hyperthyroidism

Answer 14

weight loss
agitation/anxiety
palpitations

Question 15

Hyperthyroidism treatment

Answer 15

radioactive iodine-destroy part of the gland
beta blockers-symptoms relief
Thionamides
iodides

Question 16

Hyperthyroidism in pregnancy

Answer 16

PTU for 1st trimester

methimazole for 2nd and 3rd trimester

Question 17

DOC for thyroid storm

Answer 17

PTU

Question 18

List thionamides

Answer 18

propylthiouracil (PTU)

methimazole

Question 19

MOA of thinamides

Answer 19

inhibit synthesis of thyroid hormones by blocking the oxidation of iodine in the thyroid gland

Question 20

List iodides

Answer 20

potassium iodide

Question 21

MOA of iodides

Answer 21

temporarily inhibit secretion of thyroid hormones

Question 22

potassium iodide and radioactive iodine for hyperthyroidism

Answer 22

potassium iodide should be taken ASAP after radiation to prevent thyroid cancer

Question 23

Define thyroid storm

Answer 23

decompensated hyperthyroidism

Question 24

S/Sx of thyroid storm

Answer 24

Fever
tachycardia
profuse sweating
agitation
delirum
coma
psychosis

Question 25

Treatment for thyroid storm

Answer 25

PTU
inorganic iodide therapy 
beta blockers
systemic steroid
aggressive cooling