Sexual Dysfunction

Question 1

main drug for women with sexual dysfunction

Answer 1

addyi

Question 2

What are common drug classes that causes sexual dysfunction

Answer 2

antidepressants
antihypertensives
antipsychotics
BPH medications
alcohol

Question 3

which antidepressant is least likely to cause sexual dysfunction

Answer 3

bupropion

Question 4

natural products for ED

Answer 4

yohimbe
L-arginine
panax ginseng

Question 5

Tadalafil use besides ED

Answer 5

benign prostatic hypertrophy

Question 6

Sildenafil use besides ED

Answer 6

pulmonary arterial hypertension

Question 7

PDE-5 inhibitors MOA

Answer 7

following sexual stimulation there is a local release of nitric oxide which increases cGMP and causes smooth muscle relaxation. this permits blood to flow in resulting in an erection. PDE-5 inhibitors block PDE-5 from degrading cGMP

Question 8

contraindication for PDE-5i

Answer 8

use with nitrates

Question 9

starting dose for viagra

Answer 9

50mg

Question 10

starting dose for cialis

Answer 10

10mg

Question 11

starting dose for levitra

Answer 11

10 mg

Question 12

starting dose for stendra

Answer 12

100 mg

Question 13

when to reduce dose of a PDE-5i

Answer 13

> 65 years
using alpha-blocker
severe renal or liver disease
-starting dose decrease by 50%

Question 14

Alprostadil MOA

Answer 14

it is a prostaglandin E1, a vasodilator that allows blood to flow into the cavernosal arteries, which then enlarges teh penis. it is either injected into the penis or a pellet is inserted through the urethra

Question 15

Flibanserin MOA

Answer 15

agonist activity at 5-HT1A and antagonist activity at 5-HT2A receptors