Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

NAPLEX > Asthma > Flashcards

Asthma Flashcards

1
Q

how to diagnose asthma

A

spirometry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

define fev1

A

how much air can be forcefully exhaled in 1 second

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

define fvc

A

after taking a deep breath, the max volume of air that is exhaled

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

FEV1/FVC

A

the % of total air capacity “vital capacity” that can be forcefully exhaled in one second

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Based on rescue inhaler use classify intermittent asthma

A

< 2days/wk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Based on rescue inhaler use classify mild persistent asthma

A

> 2 days/week but not daily or > 1x/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Based on rescue inhaler use classify moderate persistant asthma

A

Daily use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Based on rescue inhaler use classify severe persistant asthma

A

several times per day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

step 1 treatment for asthma

A

PRN low-dose ICS + formoterol
or
Low dose ICS when SABA is taken

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Step 2 treatment for asthma

A

daily low dose ICS
or
prn low dose ICS + formoterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Step 3 treatment for asthma

A

Low dose ICS

+ LABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Step 4 treatment for asthma

A

Mediu dose ICS

+ LABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Step 5 treatment for asthma

A

High dose ICS

+LABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

beta-2 agnoist MOA

A

bind to beta-2 receptors causing relaxation of bronchial smooth muscle which leads to bronchodilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name a SABA

A

albuterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Name a LABA

A

salmeterol

17
Q

Why do LABAs need to be combined with an ICS

A

increased risk of asthma-related deaths

18
Q

budesonide + formoterol brand name

A

symbicort

19
Q

fluticasone + salmeterol brand name

A

Advair

20
Q

Fluticasone + vilanterol brand name

A

Breo Elipta

21
Q

mometasone + formoterol brand name

A

Dulera

22
Q

major SE of ICS

A

thrush

23
Q

Leukotriene receptor antagonists (LTRA) MOA

A

inhibit leukotriene mediators of airway inflammation this reduces airway edema, contriction and inflammation

24
Q

Montelukast inhibits which leukotrienes

A

D4

25
Q

zafirlukast inhibits which leukotrienes

A

LTD4

LTE4

26
Q

Zileuton MOA

A

5-lipoxygenase inhibitor, inhibits leukotriene formation

27
Q

List LTRAs

A

montelukast
zafirlukast
zileuton

28
Q

Theophylline MOA

A

blocks phosphodiesterase, causing an increase in cyclic adenosine monophosphate (cAMP) and release of epinephrine from adrenal medulla cells this results in bronchodilation

29
Q

aminophylline to theophylline conversion

A

aminophylline contains 80% theophylline
“ATM” amino -> theo multiply
theo to amino divide by 0.8

30
Q

omalizumab MOA

A

inhibits IgE binding to the IgE receptor on mast cells and basophils

31
Q

Treatment for exercise induced bronchospasm

A

SABA

32
Q

define peak expiratory flow rate (PEFR)

A

max flow rate from a forceful exhalation, starting from fully inflated lungs

NAPLEX (65 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions