Synaptic plasticity Flashcards
synaptic plasticity
connections between neurons to change and adapt - how our brain learns and forms memories
Mechanisms of synaptic plasticity
1.sprouting
2.reruiting
3.pruning
Mechanisms of synaptic plasticity: sprouting
ability of dendrites or axons to develop new extensions or branches
Mechanisms of synaptic plasticity: rerouting
a neuron that is connected to a damaged neuron to create an alternative synaptic connection with an undamaged neuron
Mechanisms of synaptic plasticity: pruning
the elimination of synaptic connections that are not adequately activated
Long-term potentiation (LTP) (sprouting)
long-lasting enhancement of synaptic transmission due to repeated strong stimulation - memory
long term potentiation example
- neurons involved in bike riding r coactivated, continueing practicing will allow these neurons to be repeatedly coactivated
- synaptic connections between these neurons physically change - strengthening
3.memory trace forms
LONG TERM DEPRESSION (LTD)
(pruning)
long-lasting decrease in the strength of synaptic transmission and neuronal response
LTD OCCURS…
due to repeated low level stimulation of a presynaptic and a postsynaptic neuron.
similarities between LTD n LTP
both have long lasting effects, both occur at glutamate synapses