Special Senses III Flashcards

1
Q

What are the signals for spicy food?

A

Nociceptors

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2
Q

What is the chemical for spice? What is its MOA?

A

Capsaicin–Opens VR1 receptor

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3
Q

What are the 5 taste sensations?

A
Sour
Salty
Sweet
Bitter
Umami
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4
Q

True or false: At moderate concentrations of taste stimuli, sour, salty, sweet and bitter tastes can be perceived by stimulating any area containing taste receptor cells

A

True

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5
Q

Where are the taste buds on the tongue?

A

In the trenches along papilla

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6
Q

The tip of the tongue is most sensitive to what tastes? (3)

A

Sweet
Umami
Salt

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7
Q

The sides and back of the tongue are more sensitive which two tastes?

A

Sour and bitter

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8
Q

What happens if you cut the nerve to a taste bud?

A

Oh yeah, it dies

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9
Q

True or false: the basal cells can turn into taste buds

A

True

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10
Q

True or false: we all have about the same number of taste buds

A

False

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11
Q

True or false: taste has a strong genetic component

A

True

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12
Q

What is the innervation to the anterior 2/3 of the tongue?

A

C VII

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13
Q

What is the innervation to the posterior 1/3 of the tongue?

A

CN IX

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14
Q

What is the innervation of the soft palate?

A

CN VII

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15
Q

What is the innervation of the epiglottis and esophagus?

A

CN X

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16
Q

Where do all of the taste tract combine? What part of the thalamus does this area then project to?

A

Nucleus of the solitary tract, then to the ventral posterior medial nucleus of the thalamus

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17
Q

What part of the cortex senses tastes?

A

Insular taste cortex

18
Q

What is the role of the amygdala in taste?

A

Motivation of food

19
Q

How are salt and sour sensed?

A

Opens an ion channel

20
Q

How are sweet, bitter, and umami sensed?

A

G-protein coupled receptor

21
Q

Depolarization of taste cells cause what?

A

release of neurotransmitters onto primary afferent nerves.

22
Q

True or false: there is a labeled line to the taste cortex

23
Q

What is the bait-shyness (Sauce Bearnaise) phenomenon?

A

Losing taste for a food that the brain associated with sickness

24
Q

What is hypogeusia?

A

Decreased taste sensation

25
What is ageusia?
Absence of taste
26
What is parageusia?
Perversion of the sense to taste; a bad taste in the mouth
27
What is unique about CN I? (3)
Exposed Bypasses thalamus Regenerate
28
What type of neurons are the olfactory nevelets?
Bipolar neurons
29
How do we smell stuff (how do the nervelets sense odors)?
Binding of odoriferous molecule to receptor on cilia of olfactory receptor cell.
30
What are the cells that produce mucus for the olfactory bipolar cells?
Bowman's glands
31
What do odiferous molecules bind to?
G-protein coupled receptors
32
How many different functional odorant receptors in humans?
around 400
33
Olfactory neurons expressing the same type of olfactory receptor project where?
The same glomeruli
34
True or false: there is one receptor for every odor
False--An odorant might interact with several different types of olfactory receptors
35
What is the function of the neurons that project from the olfactory bulb to the gustatory cortical areas?
Olfactory and gustatory signals may be integrated here to generate the perception of flavor.
36
What is the route of the olfactory projections that go to the medial dorsal nucleus of the thalamus?
projects to the orbitofrontal cortex
37
What is the function of the orbitofrontal cortex?
This cortical area is thought to be involved in the perception and discrimination of odors
38
What is the role of the limbic system in the olfactory system?
probably mediate affective component of odors - whether odor pleasant or unpleasant
39
What is specific anosmia?
lowered sensitivity to a specific odorant even though sensitivity to other odorants seems normal
40
What is general anosmia?
Complete loss of sense of smell
41
Is hyposmia transient or chronic?
Either
42
What happens to odor sensitivity in Alzheimer's disease?
greatly diminished or distorted sense of smell