Regulation of Body fluids Flashcards
ICF accounts for what percent (fraction) of total body water?
2/3
ECF accounts for what percent (fraction) of total body water?
1/3
What are the two subdivisions of ECF, and how large are they relative to total ECF?
Interstitial fluid (~75% of ECF)
Plasma volume (~25% of ECF
What are the main cations and anions for intracellular fluid?
Cation: K
Anion: PO3, proteins
What are the main cations and anions for plasma?
Cation: Na
Anion: Cl, CO3
What is the equation for the anion gap?
Anion Gap = Na - (Cl + HCO3-)
What are the main cations and anions for interstitial fluid?
Cation: Na
Anion: Cl, CO3
What is the normal range of Na?
135-145
What is the normal [Cl]?
104
What is the normal range of bicarb?
24
What is the normal plasma [K]?
~4
Which has a higher [protein], plasma or interstitial fluid? What happens if this is reversed?
Plasma
If reversed, then edema
What allows for the difference in main cations between the intracellular fluid, and the extracellular fluid?
The presence of a lipid bilayer
What happens to ECF and ICF when giving a pt pure water?
Increases volume of both ICF and ECF, lowers osmolality of both
What would happen if you gave a pt isotonic saline?
Increase in ECF volume relative to ICF