Pancreas Flashcards
What are the two general roles of the pancreas?
Exocrine and endocrine function
What are the two protective roles that the pancreas has in it exocrine role?
Secrete bicarb and mucus
What is the exocrine digestive role of the pancreas?
Enzyme secretion
How do pancreatic secretions make it into the duodenum?
Pancreatic duct>common bile duct
What are the cells that make up the glands of the pancreas?
Acinar cells, ductal cells, and goblet cells
What is the function of acinar cells of the pancreas?
Protein synthesis
Secretion of enzymes/fluid
What is the function of ductal cells?
bicarb secretion
Ion transport
Fluid transport
What are the functions of the goblet cells of the pancreas?
Mucin secretion (hydrating, protecting, immunity)
What is the function of Trypsinogen? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of chymotrypsin? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of proelastase? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of proprotease E? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of Procarboxypeptidase B? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of Procarboxypeptidase B? Is this secreted in an inactive, or active form?
Protein digestion
Inactive
What is the function of alpha amylase? Is this secreted in an inactive, or active form?
Carb digeston
active
What is the function of carboxyl ester lipase? Is this secreted in an inactive, or active form?
Lipid digestion
Active
What is the function of lipase? Is this secreted in an inactive, or active form?
Lipid digestion
Active
What is the function of RNase? Is this secreted in an inactive, or active form?
Nucleotide digestion
Active
What is the function of DNase? Is this secreted in an inactive, or active form?
Nucleotide digestion
Active
What is the function of colipase? Is this secreted in an inactive, or active form?
Helps lipase with Lipid digestion
Active
What is the function of Trypsin inhibitor? Is this secreted in an inactive, or active form?
Inhibits trypsin
Active
What is the function of CCK and Ach in the pancreas?
Release of enzyme vesicles from the acinar cells of the pancreas
Activation of Cl channel
What is the function of VIP and CCK?
VIP enhances the release of enzymes that CCK causes