Skin Diseases Flashcards
Disease that usually appears brown-black growth on the face, chest and shoulders
Seborrheic keartosis
Other name for seborrheic keratosis
Senile wart
Causative agent for senile wart
Human Papilloma Virus (HPV)
Also known as common wart
HPV
Is verruca vulgaris contagious?
Yes
T/F: Common wart does not recurr
False
A dry, scaly plaque with an erythematous base
Actinic keratosis
T/F: Actinic keratosis is Pre-cancerous
True
Etiology of Actinic keratosis
Sun damage
Other name for Actinic keartosis
Sun burn
Actinic keratosis may lead to what type of cancer?
Basal cell carcinoma
Most common cancer in the skin
Basal cell carcinoma
T/F: Basal Cell Carcinoma has the worst prognosis.
False- it does not metastasize
A skin lesion that appeasrs as scaly, white plaques caused by rapid proliferation of the EPIDERMIS resulting to pruritus.
Psoriasis
Pathognomonic sign of Psoriasis
Auspitz sign
What is auspitz sign?
Presence of bleeding spot during scratching
Treatment for Psoriasis
STEROIDS
Infection of psoriasis leads to?
Monroe’s abscess
Monroe’s abscess is caused by?
S. aureus
A contagious disease that affects superficial skin with blisters but if left untreated can lead to acute glomerulonephritis due to Strep pyogenes
IMPETIGO
Causative agent for impetigo
S. aureus
S. pyogenes
Treatment of Impetigo
Topical antibiotic
Fluid filled with symptoms lesion
Blisters
Fluid filed with asymptomatic lesion
Vesicle
Bulla
Transmission of impetigo
Air-borne
skin contact
Disease characterized by a progressively enlarging scar due to an abnormal accumulation of collagen.
Keloid
Other name for Keloid
Proud flesh
2 most important protein for wound healing
Collagen
Elastin
Too much collagen during scar formation leads to?
Keloid
What is cicatrixation?
Scar formation
What is the first collagen present in wound healing?
Type 3
What is the most abundant collagen in wound healing?
Type 1
An autoimmune connective tissue disease due to overproduction of collagen.
Sclerodema
Signs and symptoms of scleroderma
Facial erythema Fever Reynaud's phenomenon Joint pain Photophobia
What is Reynaud’s phenomenon?
Color blue palm and sole due to constriction of blood vessel
Disease caused by allergic reaction in drugs
Erythema multiforme
Erythema multiforme are commonly seen in what areas?
Skin
Oral mucosa
Eye
Genital area
Drugs for EM
Sulfonamides
Penicillins
Barbiturates
Treatment for EM
Steroids
A severe form of EM
Steven-Johnson syndrome
Clinical appearance of EM
Painful red or purplish rash and blisters
The most severe form of EM
Toxic ependymal necrolysis
Characterized by widespread erythema, necrosis and bullous detachment of the epidermis and mucous membranes, resulting in exfoliation and possible spots or even death.
Toxic ependymal necrolysis
What is the pathognomonic sign of erythema multiforme?
Bull’s eye/Target/Iris lesion
What disease mimics EM?
Lyme’s disease
Lyme’s disease is caused by?
Tick bite
Causative agent for Lyme’s disease
Borrellia burgdorferi
Living thing that carries infection is called?
Vector
Non-living that carries infection
Fomites
Diseasecaused by disruption of desmosal attachment of epidermal cells by antibodies producing blisters on the skin and oral mucosa
Pemphigus
is the loss of intercellular connections, such as desmosomes
Acantholysis
Main organ affected by Pemphigus
Epidermis
Histologic finding of Pemphigus
Tzanck cells
Pathognomonic sign of Pemphigus
Nikolsky sign
is a skin finding in which the top layers of the skin slip away from the lower layers when rubbed.
Nikolsky sign
Treatment of Pemphigus
PUVA
Psoralene Ultra Violet A
Autoimmune disease against basement membrane
Pemphigoid
most common type of pemphigoid with presence of blisters on arms and legs.
Bullous`pemphigus
Type of pemphigoid where there are blisters on mucous membranes
Cicatrical Pemphigus
Location of Cicatrical pemphigus
Mouth and Eyes
Type of pemphigoid present during pregnancy usually 2nd to 3rd trimesters
P. Gestations
A condition that can cause swelling and irritation of the skin.
Lichen planus
Lichen planus in the oral cavity affects
RETE PEGS triggered with emotional stress
Clinical manifestation of lichen planus
Purplish
Itchy
Flat bumps
Oral manifestation of Lichen planus
Wickham striae on buccal mucosa
Histological appearance of Lichen planus
Saw-tooth appearance with Civatte or Colloid bodies
What is Wickham striae?
Lace-like white lesion