Gastrointestinal and Hepatobiliary Diseases Flashcards

1
Q

What is a syndrome?

A

Collection of disease

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2
Q

any harmful deviation from the normal structural or functional state of an organism, generally associated with certain signs and symptoms

A

Disease

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3
Q

autoimmune disease of the salivary, lacrimal glands, and synovial membrane

A

Sjogren syndrome

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4
Q

Sjogren triad

A

Xerostomia
Keratoconjunctivitis sicca
Rheumatoid arthritis

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5
Q

Other name of sjogren syndrome

A

Sicca syndrome

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6
Q

Cell responsible for an autoimmune disease

A

T-cell

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7
Q

Main cause of an autoimmune disease

A

Stress

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8
Q

Organs affected in sicca syndrome

A

Salivary gland
Eyes
Joint

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9
Q

What are the signs and symptoms of Reiter’s syndrome?

A

Arthritis
Conjunctivitis
Urethritis

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10
Q

What are the signs and symptoms of Mikulicz syndrome?

A

Conjunctivitis

Xerostomia

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11
Q

Difference between Reiter’s and Sicca syndrome?

A

Sicca affects: Eyes, Joints, Salivary gland while

Reiter’s affects: Eyes, Joints and Urethra

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12
Q

True or false: Sjogren’s syndrome is also associated with mikulicz syndrome.

A

True

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13
Q

Syndromes associated with sicca syndrome

A

Reiter’s syndrome

Mikulicz syndrome

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14
Q

A benign tumor of the PAROTID GLAND

A

Warthin’s tumor

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15
Q

Other name of warthin’s tumor

A

Papillary cystadenoma lymphomatosum

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16
Q

Major salivary gland common to diseases

A

Parotid gland

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17
Q

Most common salivary gland tumor

A

Mixed tumor

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18
Q

Other name of mixed tumor

A

Pleomorphic adenoma

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19
Q

most common malignancy of major salivary glands

A

Mucoepidermoid carcinoma

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20
Q

most common malignancy of minor salivary gland

A

Adenoid cystic carcinoma

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21
Q

Histologic feature of adenoid cystic carcinoma

A

Cheese-like

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22
Q

Characterized by lacerations of the esophagus

A

Mallory-weiss syndrome

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23
Q

Manifestation of mallory-weiss syndrome

A

Melena

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24
Q

Black stool in the blood is due to?

A

Degradation of blood by acid

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25
Bleeding below the stomach would manifest?
Hematochezia
26
Melena- | hematochezia-
Melena- black stool | Hematochezia- red stool
27
T/F: Melena and Hematochezia solidifies together with stool
False- does not solidify
28
syndrome where there is ruptured esophagus that causes massive GI hemorrhage
Boerhaave syndrome
29
Sign and symptoms of boerhaave syndrome
Sever vomiting | Straining
30
A reflux of acid content due to histamine released of the stomach.
Gastroesophageal reflux disease
31
GERD is always associated with?
Barrett's esophagus
32
Barrette's esophagus is what type of cellular adaptation?
Metaplasia
33
Change of epithelial cells in barrett's esophagus
Squamous to columnar
34
Barrett's esophagus left untreated leads to?
Adenocarcinoma
35
Oral manifestation of GERD
Erosion on the lingual surface of the molars
36
Drugs for GERD
Antihistamine (H2 BLOCKER, cimetidine) Antacids Proton-pump inihibitor
37
Complication of Barrett's esophagus
Hemorrhage Stricture Adenocarcinoma Ulcerations
38
Most sever complication of barrett's esophagus
Adenocarcinoma
39
Erosion on the lingual of incisors
Bulimia nervosa
40
caused by early activation of pancreatic enzyme resulting in auto-digestion
Acute pancreatitis
41
Acute pancreatitis undergoes what type of necrosis?
Enzymatic fat necrosis
42
Blood test result of Acute pancreatitis
Increased serum amylase and lipase | Decreased calcium
43
Enzyme that dominates in acute pancreatitis
Lipase
44
It is characterized by yellowness of tissues due to excess serum Bilirubin in the blood.
Jaundice
45
Other name for Jaundice
Icterus
46
Jaundice in brain
Kernicterus
47
Specific art of brain where jaundice occurs
Basal ganglia o brain
48
True or false. Bilirubin crosses the placenta
True
49
Jaundice in newborn affects?
Brain
50
Causes of jaundice
Hepatocellular Hemolytic Obstructive Pancreatic carcinoma
51
Bilirubin conjugate with what element of blood
RBC
52
Other name of hemolytic in jaundice
Hemolytic anemia
53
Other name of obstructive jaundie
Cholelith
54
gives pigment to bruises
Biliverdin
55
a pigment accumulation in kupffer cell which is a sign of liver injury.
CEROID
56
It is characterized by excessive scarring and nodule formation
cirrhosis
57
Causes of cirrhosis
``` Alcoholism Viral hepatitis Hemochromatosis Wilson's disease Dubin-johnson's disease ```
58
Most common cause of cirrhosis
aLcoholism
59
Liver cirrhosis due to excessive iron in the liver
Hematochromatosis
60
Liver cirrhosis due to excessive copper in the liver
Wilson's disease
61
pathognomonic sign of wilson's disease
Keyser-fleischer ring
62
Keyser-fleischer ring
Borderof the iris is color green due to excess copper
63
Liver cirrhosis due to excessive melanin
Dubin-johnson's disease
64
Other name for Dubin-johnson's disease
Black liver disease
65
Blood tests needed for cirrhosis
Increased AST or SGOT | Increased ALT or SGPT
66
AST stands for? | ALT stands for?
aspartate trans-aminoferase | alanine trans-aminoferase
67
SGOT stands for? | SGPT stands for?
Serum glutamic oxaloacetic transaminoferase | Serum glutamate pyruvate transaminoferase
68
Most common viral hepatitis
Hepatitis A
69
Route of transmission of Hepatitis a
Oral-fecal/ oral-anal | GI tract
70
Causative agent for Hepatitis A
Picornavirus
71
Most common blood-borne
Hep B
72
Causative agent for Hep B
Hepadnavirus
73
Sterlization process that could kill Hep B
Moist-heat
74
Duration of Medication for Hep B
Lifetime intake
75
Most difficult virus to eradicate
Hepadnavirus
76
most common hepatitis in blood transfusion
Hep C
77
causative agent for Hep C
Flavivirus
78
Most difficult to diagnose Hepatitis
Hepatitis C
79
Hepatitis with slowest progress
Hepatitis C
80
Every hepatitis have a vaccine except?
Hepatitis C
81
Recurrent of HepB
Hepatitis D
82
Hepatitis associatedwith ACUTE LIVER FAILURE
Hepatitis E
83
Sterilizing agent used in the hospital to eliminate Hep B
Sodium hypochlorite
84
Causative agent for Hep D
Deltavirus
85
Causative agent for Hep E
Calicivirus
86
the marker of Hepa B
HbSAg
87
Indications that the virus is multiplying in the body
HbEAg and HbSAg
88
Carrier of Hep B
HbSAg and anti-HbSAg
89
Indicates chronic hepatitis and patient is contraindicated for blood transfusion
HbCAg
90
An autosomal dominant characterized by dark, freckle-like spots that appear on the skin, lips and oral mucosa.
Peutz-Jeghers syndrome
91
Other name for peutz jeghers syndrome
Hereditary Intestinal Polyposis Syndrome
92
What is a polyp?
Inflamed blood vessel
93
Autosomal means?
Affects the 1st to 22nd paired chromosome
94
X-linked means?
Affects the 23rd paired chromosome
95
Requires both genes of the parents to affect the child
Recessive
96
Requires at leastone gene to affect the child
Dominant
97
A chronic inflammatory bowel disease that results to cobblestone appearance
Chron's disease
98
A congenital disease that affects COLON
Hirschprung's disease
99
An autoimmune disease that results to intolerance of gluten proteins present in wheat, barley and rye.
Celiac disease
100
An autoimmune disease affecting children that results to intolerance of gluten proteins present in wheat, barley and rye.
Gee-herter's disease
101
Oral manifestation of Celiac disease
Glossitis