Endocrine Disorders Flashcards
Disease characterized by hypoactivity of thyroid gland.
Hypothyroidism
(Increase, decrease) Calcium in Hypothyroidism
Decreased
Signs and symptoms of Hypothyroidism
Weight gain
retarded growth
Bradycardia
Sensitivity to cold temperature
Reason why there is weight gain in hypothyroidism
Decreased catabolic rate
Reason why there is bradycardia in hypothyroidism
decreased metabolism due to decreasedoxygen demand
Clinical manifestations of Hypothyroidism
Myxedema
Cretenism
Hashimoto’s disease
Form of hypothyroidism in adult
Myxedema
Form of hypothyroidism in children
Cretenism
Oral finding in cretenism
Macroglossia
Prolonged retention of primary teeth
end of primary dentition
12 years old
An autoimmune disease that attacks the thyroid
Hashimoto’s thyroiditis
Hashimoto is associated with?
High blood cholesterol
Positive nitrogen balance
Decreased protein bound iodine
Decreased iodine uptake by the thyroid gland
Most common hypothyroidism
Hashimoto’s thyroiditis
Disease characterized by hyperactivity of thyroid gland
Hyperthyroidism
Signs and symptoms of hyperthyroidism
Weight loss
Irritability
nervousness
tremors
Most common sign of hyperthyroidism
Exophthalmus
Oral finding of hyperthyroidism
Early loss of primary teeth
What is a tremor?
uncontrolled muscle activity
Reason why there is early loss of primary teeth
decreased bone support
Clinical manifestation of Hyperthyroidism
Grave’s disease
Plummer disease
Autoimmune disease of which antibodies bind to TSH receptors
Grave’s disease
Complication of grave’s disease
Pre-tibial myxedema
Disease with nodular growth or adenoma of the thyroid
Plummer disease
most contraindicated in hyperthyroidism
Epinephrine
Reason why epinephrine is contraindicated in px with hyperthyroidism
Thyrotoxicosis
A condition in which one or more of the parathyroid glands become overactive and secretes too much PTH
Hyperparathyroidism
Hyperparathyroidism causes?
Cystic bone lesion
Nephrocalcinosis
Metastatic calcifications
Other name of hyperparathyroidism
Von recklinghausen’s disease of the bone
Other name for cystic bone lesion
Central giant cell granuloma
Central giant cell granuloma is associated with?
Ameloblastoma
Accumulation of calcium nephron
Nephroliths
most common organ affected during metastatic calcification
Lungs
Metastatic calcification in lungs leads to?
Cancer of the lungs- Oat cell carninoma
Radiographic finding in hyperparathyroidism
Ground-glass
Absence of Lamina Dura
Dental concern of Hyperparathyroidism
Bone fracture
Most common cancer of the lungs
SSC
Clinical manifestation of hyperparathyroidism
Primary
Secondary
Hyperparathyroidism that is caused by cancer
Primary hyperparathyroidism
Hyperparathyroidism as a result of chronic renal disease or kidney failure
Secondary hypeparathyroidism
A condition of decreased secretion or activity of PTH.
Hypoparathyroidism
Common procedure that results to Hypoparathyroidism
Accidental surgical removal of thyroid gland
Hypoparathyroidism is associated with
Digeorge syndrome
Condition due to hyposecretion of GH
Dwarfism
Characteristics of dwarfism
Abnormally short height
Smaller maxilla and mandible
Delayed eruption of permanent teeth
A condition where the child has a normal size of torso but abnormally short extremities
Achondroplastic dwarfism
Overproduction of GH before epiphyseal plates closure
Gigantism
Overproduction of GH afterepiphyseal plates closure
Acromegaly
Oral manifestation of acromegaly
Large tongue
Condition where there is lack of anterior pituitary gland functioning caused by ischemic necrosis due to blood loss and hypovolemic shock during and after childbirth
Sheehan’s disease
Other name for sheehan’s disease
Postpartum pituitary gland necrosis
Sheehan’s disease can result to?
Addison’s disease
Myxedema
Hypogonadism
Rare tumor formed from adrenal medulla chromaffin cells
Pheochromoytoma
Cancer in childrenthat affects the adrenal medulla
Pheochromoytoma
Hallmark of Pheochromoytoma
Hypertension
Pheochromoytoma associated with
Sturge-weber syndrome
Multiple endocrine neoplasia
A rare disorder characterized y the association of facial birthmark called port-wine stain that follows the trigeminal pathway, neurologic disorder and eye abnnormalities
Sturge-weber syndrome
other name for sturge-weber syndrome
Encephalotrigeminal angiomatosis
What is a glaucoma?
High occular pressure due to increase aqueous in the eye
Ganglion affected in Encephalotrigeminal angiomatosis
Semilunar ganglion
Radiographic appearance of Sturge-weber syndrome
Tram-line calcifications in the skull
Venous malformation of Encephalotrigeminal angiomatosis
Leptomeninges of the cerebral cotex
Neurologic disorder of sturge-weber syndrome
Mental retardation
Hemiparesis
Seizure disorder
What is hemiparesis?
weakness of one side of the body
An autosoomal dominant multiple endocrine neoplasia affects?
Parathyroid
Pancreas
Pituitary
caused by medullary thyroid carcinoma, phechromocytoma and parathyroid hyperplasia
MEN II
Other name for MEN II
Sipple disease
MEN most associated with pheochromocytoma
MEN II
Patients with this condition have no phenotypic abnormalitis of mucosal neuromas
MEN II-A
Patients with this condition have MARFANOID HABITUS
MEN IIB
Most common malignant tumor found in CHILDREN
Neuroblastoma
Disease that targets ADRENAL gland that can metastasize to LIVER
Neuroblastoma
Disease caused by a deficiency in aldosterone or cortisol
Addison’s disease
Pathognomonic sign of addison’s disease
Melanosis
bronze-color skin
Type of addison disease caused by autoimmune or infection
Primary addison’s disease
Tye of addison’s disease due to decrease of ACTH from pituitary gland
Secondary addison’s disease
The test to differentiate primary to secondary addison is
ACTH stimulation test
Disease caused by an excessive aldosterone production
Conn’s disease
Disease due to excessive STEROIDS production
Cushing’s disease
Pathognomonic sign in Cushing’s disease
Buffalo hump
Moon face
Dental concern in Cushing’s disease
Infections
What are Steroids?
anti-inflammatory
anti-stress
Side effect of STEROIDS
Immunosuppressant
Weight gain
A group of metabolic disorder characterized by high blood sugar levels over a prolonged period
Diabetes mellitus
Signs and symptoms of DM
Polyphagia
Polyuria
Polydypsia
Chronic condition in DM which the pancreas produces little or no insulin
DM I
Other name of DM I
Juvenile diabetes
Insulin-dependent
Treatment of DM I
lifetime Insulin shot
onset of Insulin shot
12-24 hours
Chronic condition in DM that affects the way the body metabolizes sugar (glucose) caused by deficient insulin.
DM II
Other name for DM II
Non-insulin dependent
Predisposing factor of DM II
Amyloidosis
Pathognomonic sign of DM II
Ketone breath due to ketoacidosis
Treatment of DM II
Good diet
Metformin
Exercise
can DM I becomes DM II
No
can DM II becomes DM I
Yes
Ketone bodies are excereted by the body through?
Expiration
DM due to excessive steroids intake
DM III
DM due to hormonal imbalance
DM IV
Other name for DM IV
Gestational diabetes
Complications of DM
Cardiovascular
Retinopathy leading to glaucoma
Nephropathy
What is the most common type of DM?
Type II
What is the most common cause of death of DM
Cardiovascular
What is the pathognomonic sign of DM?
Ketone breath
What is the dental concern for patients with DM?
Poor wound healing due to increase sugar which tends to increase infection
A rare condition when there is deficiency in ADH.
Diabetes insipidus
Signs and symptoms of Diabetes insipidus
Polyuria
Polydypsia
Treatment of diabetes insipidus
Desmopressin
Artificial vasopressin
Desmopressin
Etiologies of metabolic acidosis
Diabetes
Starvation
Lactic acidosis
Severe dehydration
Clinical manifestation of metabolic acidosis
Dyspnea
Nausea
Vomiting
Etiologies of Metabolic alkalosis
Vomiting Diuretic use Cushing syndrome Conn's Exogenous steroids
Clinical manifestation of Metabolic alkalosis
Confusion Delirium Coma Arrythmia Hypotension