Nervous System diseases-Hypersensitivity Flashcards
Form of headache and is the primary disorder of the brain caused by dysfunction of brainstem papthway.
Migraine
Cause of migraine
Stress
The most common demyelinating disease
Multiple sclerosis
A demyelinating disease of the CNS due to damage of white mater.
Multiple sclerosis
Most common affected nerve in multiple sclerosis
CN II
a relative afferent pupillary defect indicating a decreased pupillary response to light in the affected eye
marcus-gunn
Multiple sclerosis triad
Scanning speech
Intention tremor
Nystagmus
Dancing eyes
Nystagmus
A demyelinatingdisease of PNS in which myelin sheath of neurons is damaged
Guillain-barren syndrome
Most common complication after parotidectomy due to damaged of auriculotempora nerve
Frey syndrome
Other name for Frey syndrome
Gustatory sweating
Sign of frey syndrome
Sweating while eating on the temporal area
characterized by rapid degeneration of motor neurons in the spinal cord
Amyotrophic lateral sclerosis
Pathognomonic sign of Amyotropic Lateral sclerosis
Hatchet-Face
Appearance of the face in anxiety reaction
Hatchet-face
The most common cause of dementia due to degeneration of neurons in the brain.
Alzheimer’s disease
The most common affected part of the brain in alzhaimer’s disease is
Hippocampus
Characterized by degeneration of neurons in the basal ganglia leading to deficiency in dopamine in CNS
Parkinson’s disease
Histologic finding in Parkinson’s disease
Lewy bodies in substancia nigra
Treatment of Parkinson’s disease
L-dopa with carbidopa
Complication in taking medicines for Parkinson’s disease
Schizophrenia
Disease that cuases dementia characterized by the degeneration of striatal neurons, affecting cortical and basal ganglia function.
Huntington’ disease
Disease due to an infacrt of the parts of the brain
Stroke
Other name for stroke
Cerebral infarction
Cerebrovascular accident
Signs and symptoms of stroke
Sudden paralysis and numbness of the body (contralateral)
What is the most common structure involved in stroke?
Middle cerebral artery
Other name for middle cerebral artery
Lenticulostriae
What is the origin of stroke?
Deep vein thrombosis
Types of hypersensitivity reactions
Anaphylaxis
Cytotoxic type
Immune-complex
Delayed/cell-mediated hypersensitivity
Mediator of Type1 hypersensitivity
IgE
Most common type 1 hypersensitivity
Hives
Sign of Hay fever
Coryza
Coryza means
Runny nose with watery eyes
Types of hypersensitivity 1
Hay fever
Asthma
Hives
Other name of Hives
Wheals
Mediator of type II hypersensitivity
IgG and IgM
Also known as tear drop erythrocyte
Autoimmune hemolytic anemia
Blue baby
Erythroblastosis fetalis
Examples ofTypeII hypersensitivity
Autoimmune hemolytic anema
Erythroblastosis fetalis
Lichen planus
Mediator of type III hypersensitivity
Ag-Ab complex
Cell for the Ag-Ab complex
B-cell
Hypersensitivity due to incompatible antigen in the body
Arthus reaction
Hypersensitivity that develops 1-3 weeks after transfusion of blood
Serum sickness
Hypersensitivity that gives Butterfly rash
SLE
Rheumatic fever is what type of hypersensitivity
Type 3
Rheumatic fever affects what organ
Heart (all layers)
Rheumatic fever is associated with?
joint disease
It is the defense in our body against parasites, bacteria and fungi.
Delayed/cell-mediated hypersensitivity
Delayed/cell-mediated hypersensitivity involves what cells?
NK cells Macrophages
Mediator in type IV hypersensitivity
None
Types of type IV hypersensitivity
Tuberculosis
Contact dermatitis
transplant infection
EM
Common cause of transplant failure
infection
Most common hypersensitivity in emergency room?
Type 1 (hives)
Most common hypersensitivity in dental practice?
Type IV contact dermatitis
Positive to tuberculin test indicates what type of hypersensitivity
Type IV
Anemia that affects all blood cells
Aplastic anemia
Other name for tuberculin test
Montoux test
Diseases with histologic appearance of Councilman bodies including hyaline bodies
Yellow fever
Viral hepatitis
Diseases with histologic appearance of Negri bodies
Rabies
Diseases with histologic appearance of Cowdry type-A bodies
Yellow fever
Herpes virus
Diseases with histologic appearance of Cowdry type B bodies
Adenovirus
Poliovirus
Diseases with histologic appearance of Lewy bodies
Parkinson’s disease
Diseases with histologic appearance of Hirano bodies
Alzheimer’s disease
Diseases with histologic appearance of Howell-jelly bodies
Megaloblastic anemia
Hemolytic anemia
Diseases with histologic appearance of Hectoid bodies
Sickle cell anemia
Diseases with histologic appearance of heinz bodies
Thalassemia
Diseases with histologic appearance of Mallory bodies
Cirrhosis
Diseases with histologic appearance of Psammoma bodies
Dystrophic calcification in meningioma
Papillary serous cystadenoma ovary
Diseases with histologic appearance of Lipschutz bodies
Herpes simplex infection
Diseases with histologic appearance of Zera bodies
Schwann cell degeneration
Diseases with histologic appearance of Creola bodies
Asthma
Diseases with histologic appearance of Warthin-frinkeldey bodies
Measles
Diseases with histologic appearance of Zenker’s waxy hyaline masses
Typhoind fever
Disease having pathognomonic sign of “Chvostek sign”
Acute hypocalcemia
Disease having pathognomonic sign of “Trousseau sign”
Acute hypocalcemia
Disease having pathognomonic sign of “Risus sardonicus”
Tetanus
Disease having pathognomonic sign of “Cullen sign”
Pancreatitis
Disease having pathognomonic sign of “Grey-turner’s sign”
Pancreatitis
Disease having pathognomonic sign of “Kernig sign”
Meningitis
Disease having pathognomonic sign of “Murphy’s sign”
Cholecystitis
Disease having pathognomonic sign of “Levine’s sign”
Angina pectoris
Myocardial infarction
Disease having pathognomonic sign of “Homan’s sign”
Thrombophlebitis
Disease having pathognomonic sign of “Watery-rice stool”
Cholera
Disease having pathognomonic sign of “Ribbon-like stool”
Hirschsprung’s
Disease having pathognomonic sign of “Bloody-mucoid stool”
Amoebiasis
Tapping of facial nerveelicits abnormal muscle contraction on other side of the face ,is what pathognomonic sign?
Chvostek sign
Occlusion of brachial artery induces wrist spasm,is what pathognomonic sign?
Trousseau sign
Sustained spasm of facial muscle,is what pathognomonic sign?
Risus sardonicus
Ecchymosis around umbilicus ,is what pathognomonic sign?
Cullen’s sign
Flank ecchymosis ,is what pathognomonic sign?
grey-turner’s sign
Bend hip and knee then when flexing the knee, it produces pain ,is what pathognomonic sign?
Kernig’ssign
Hesitation on inspiration if gallbladder is palpated ,is what pathognomonic sign?
Murphy’s sign
Clutching of fist on the chest
Levine’s sign
Bend knee, dorsiflex ankle and pain at popliteal area ,is what pathognomonic sign?
Homan’s sign