Blood-Lymphatics Flashcards

1
Q

There is decreased number of platelets

A

Thrombocytopenia

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2
Q

The most common type of bleeding disorder

A

Thrombocytopenia

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3
Q

Amount of platelets to be diagnosed of thrombocytopenia

A

50,000 platelets

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4
Q

Platelet deficiency is associated with?

A

Idiopathic thrombocytopenic telangiectasia
Acute myelogenous leukemia
Aplastic anemia

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5
Q

organ defective in aplastic anemia

A

Bone marrow

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6
Q

An X-linked recessive disorder of the blood

A

Hemophilia

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7
Q

A deficiency in Clotting factor VIII

A

Hemophilia A

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8
Q

Most common hemophilia in males and children

A

Hemophilia A

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9
Q

Laboratory test for Hemophilia A

A

PTT

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10
Q

Deficiency in clotting factor IX

A

Hemophilia B

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11
Q

other name for hemophilia A

A

Classic hemophilia

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12
Q

other name for hemophilia B

A

Christmas disease

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13
Q

Clotting time and bleeding time of Hemophilia A

A

Increased Clotting time

Normal bleeding time

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14
Q

Clotting time and bleeding time of Hemophilia B

A

Normal clotting time

Normal bleeding time

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15
Q

Deficiency in clotting factor XI

A

Hemophilia C

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16
Q

What is the test that differentiates hemophilia A to B

A

PTT test

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17
Q

Caused by malabsorption of FATS which results to Decreased in blood clotting factor II, VII, IX, X

A

Vitamin K deficiency

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18
Q

Laboratory test for Vitamin K deficiency

A

Prolonged PT

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19
Q

Dental concern in patient with Vit. K deficiency

A

Profuse bleeding

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20
Q

Deficiency in vWF

A

Von willebrand disease

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21
Q

most common hereditary bleeding disorder

A

Von willebrand disease

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22
Q

bleeding time of Von Willebrand

A

Increased bleeding time

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23
Q

Features of von willebrand disease

A

Qualitative platelet defect
vWF allows adhesion of platelets to collagen
it affects platelet plug and coagulation cascade
autosomal dominant

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24
Q

characterized by uncontrolled proliferation of an abnormal monoclonal cell of either MYELOID or Lymphocytic

A

Leukemia

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25
Q

Dental concern in patients with anemia

A

Profuse bleeding due to Thrombocytopenia

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26
Q

most severe type of leukemia

A

Acute lymphocytic leukemia (ALL)

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27
Q

ALL commonly affects?

A

CHILDREN

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28
Q

Histologic cell in in ALL

A

Null cells

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29
Q

What are null cells?

A

WBC without substance

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30
Q

Lymphocytic anemia affects what WBC?

A

Lymphocyte

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31
Q

Most common type of leukemia in adult

A

Acute Myeloid Leukemia

32
Q

Histologic cell found in AML

A

Aeur rods may be observed in blastcells

33
Q

Monoclonal means?

A

cell produced by another cell

34
Q

WBC affected by myeloid leukemia

A

Either BASOPHILS, NEUTROPHILS,EOSINOPHILS and monocyte

35
Q

WBC most commonly affecetd by cancer?

A

Monocyte

36
Q

Leukemia with poorest prognosis

A

Acute lymphocytic leukemia

37
Q

Least malignant leukemia

A

Chronic lymphocytic leukemia

38
Q

Histologic cell in CLL

A

Smudge cells

39
Q

Leukemia associated with philadelphia chromosome

A

Chronic myeloid leukemia

40
Q

What is philadelphia chromosome?

A

Translocation of chromosome 9 with 22

41
Q

Rarest type of leukemia

A

Aleukemic leukemia

42
Q

What is the most common drug used to treat leukemia?

A

Cyclosporine

43
Q

Cyclosporine is a what kind of drug?

A

Immunosuppressant by suppressing bone marrow

44
Q

Disease characterized by enlarged lymph nodes

A

LYMPHOMA

45
Q

Lymphoma that mainly affects T-cells

A

Hodgkin’s Lymphoma

46
Q

Causative agent for HL

A

Reed-stenberg

47
Q

Other name for reed-sternberg

A

Dorothy-reed

48
Q

Most common type of HL

A

Nodular sclerosis

49
Q

Type of HL shows Pautrier Abscess

A

Mycosis Fungoides

50
Q

two types of HL

A

Nodular sclerosis

Mycosis fungoides

51
Q

Other name for Mycosis Fungoides

A

Alibert-bazin syndrome

52
Q

Lymphoma that affects B-cells

A

Non-Hodgkin’s lymphoma

53
Q

Causative agent of non-hodgkin’s lymphoma

A

EBV

54
Q

Signs and symptoms of Non-hodkin’s lymphoma

A

night sweats, malaise, fatigue, and solid tumors

55
Q

Type of lymphoma that is 95% common in AFRICAN nations.

A

Burkitt’s lymphoma

56
Q

One complication of AIDS

A

EBV

57
Q

Burkitt’s lymphoma is associated with what leukemia?

A

Acute lymphocytic anemia

58
Q

Difference between ALL and Burkitt’s lymphoma

A

Burkitt’s affects lymph nodes

ALL does not affect lymph nodes

59
Q

What is the radiographic appearance of burkitt’s lymphoma?

A

Moth-eaten

60
Q

What is the histologic appearance of burkitt’s lymphoma?

A

Starry-sky effect

61
Q

Disease with abnormal proliferation of Monoclonal plasma cells

A

Multiple myeloma

62
Q

Other name for multiplemyeloma

A

Plasma myeloma

63
Q

Presence of Bence-Jones proteins in urinalysis

A

Multiple myeloma

64
Q

CBC of multiple myeloma

A

Decreased RBC, WBC, and platelets except PLASMA cell

65
Q

Radiographic appearance of multiple myeloma

A

Multiple-punched out

66
Q

Multiple myeloma mostly affects?

A

Skull

67
Q

Disease with a very low levels of antibdies results from a failure of B-cells to differentiate

A

Bruton’s Agammaglobulinemia

68
Q

Disease with a decreased number of antibodies present due to slow antibody production.

A

Transient hypogammaglobulinemia

69
Q

Disease deficient in B-cell

A

Transient hypogammaglobulinemia

70
Q

Disease deficient in T-cells resulting from a failure of the third and fourth branchial pouches to develop normally.

A

Digeorge syndrome

71
Q

Digeorge syndrome is the absence of what chromosome?

A

22

72
Q

Organs affected in Digeorge syndrome

A

Thymus gland and parathyroid glands

73
Q

Oral manifestation of Digeorge syndrome

A

Palata cleft

74
Q

Most severe immunodeficiency disease due to absence of both b-cells and T-cells in the body.

A

Severe combined immunodeficiency syndrome

75
Q

Treatment in Severe combined immunodeficiency syndrome

A

Bone marrow transplant