Rheumatology 17 - Paget's Disease Flashcards
1
Q
define Paget’s
A
excessive and disorganised bone turnover
patchy areas of high density sclerosis or low density lysis
particularly axial skeleton
2
Q
presentation of Paget’s disease
A
bone pain
bone deformity
hearing loss
fractures
3
Q
x ray findings x 4 Paget’s
A
bone enlarged + deformed
osteoporosis circumscripta
cotton wool skull
v shaped long bone defects
4
Q
bloods with Paget’s
A
isolated ALP rise
5
Q
treating Paget’s
A
bisphosphonates
NSAIDs
supplement vit D calcium if necessary
monitor ALP for progresss
6
Q
2 key complications of Pagets
A
osteosarcoma (v bad)
x ray
spinal stenosis + cord compression
MRI
