Endocrinology 12 - Diabetes Insipidus Flashcards

1
Q

nephrogenic causes diabetes insipidus

A
lithium
hypokalaemia
hypercalcaemia
intrinsic kidney disease
genetic
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2
Q

central causes diabetes insipidus x5 (1 common link)

A

brain:

tumour, injury, infection, surgery, radiotherapy, malformations

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3
Q

5 presenting featuresof diabetes insipidus

A
hypernatraemia
polyuria
polydipsia
dehydration
postural drop
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4
Q

3 tests for diabetes insipidus when supsected

A
urine osmolality (low)
serum osmolality (high)
water deprivation test
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5
Q

describe the 3 outcomes of water deprivation test

A

8 hours urine concentrated (i.e. high osmolality) = psychogenic polydipsia

urine concentrates to high osmolality after desmopressin = central cause

doesn’t = nephrogenic

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