Infectious Diseases 2 - Antibiotics

Question 1

what should you always say whenever mentioning antibiotics

Answer 1

following local guidelines

Question 2

cell wall inhibiting Abx x5

Answer 2

beta lactams-penicillin, carbapanem, cephalosporin

vancomycin
teicoplanin

Question 3

folate metabolism inhibitors x2 abx

Answer 3

sulfamethoxazole
trimethoprim

co trimoxazole is a combo

Question 4

anaerobe specific abx

Answer 4

metronidazole

Question 5

3 abx groups inhibiting protein synth

Answer 5

macrolide - ‘mycins
tetracycline - doxy
choramphenicol

Question 6

what should be borne in mind with penicillin allergy?

Answer 6

very few are genuine - you must ask exactly what happened + check wasn’t just a side-effect like diarrhoea or small rash

Question 7

6 steps in Abx escalation and what do they each cover?

Answer 7

1. amoxicillin - strep, listeria, enterococcus
2. co amoxiclav - staph, haemophilus, e coli
3. tazocin - pseudomonas
4. meropenem - ESBLs
5. vancomycin - MRSA
6. clarithromycin or doxy - atypicals