Haematology 5 - Thalassaemia Flashcards
1
Q
define thalassaemia
A
defect in globins
auto recessive
2
Q
signs + symptoms of thalassaemia
A
prominent forehead + cheekbones splenomegaly gallstones jaundice pallor microcytic anaemia
3
Q
diagnosing thalassaemia
A
FBC
electrophoresis
DNA screen
4
Q
eventual consequence of thalassaemia and treatment
A
iron overload
thus symptoms similar to haemochromatosis
5
Q
general principles of treating thalassaemia
A
transfusions iron chelation splenectomy BM transplant monitor complications + FBC
