Renal 8 - Rhabdomyolysis

Question 1

4 things released in rhabdomyolysis

Answer 1

CK
myoglobin
potassium
phosphate

Question 2

risks x 2 with rhabdomyolysis

Answer 2

AKI from toxic myoglobin

arrhythmia from high potassium

Question 3

causes x 4 of rhabdomyolysis

Answer 3

prolonged immobility
extremely rigorous extreme exercise
crush injuries
seizures

Question 4

signs of rhabdomyolysis

Answer 4

muscle aches
oedema
fatigue
confusion
red brown urine

Question 5

investigations in rhabdomyolysis

Answer 5

CK raised in first 12 hours and takes 3 days to fall

urine dip blood+ (myoglobin)

U+E (raised K+, creat high)

ECG - check rhythm

Question 6

management of rhabdomyolysis

Answer 6

IV fluids (flush toxins)
consider through seniors:

• IV sodium bicarb
• IV mannitol

treat complications, especially high potassium