Rheumatology 13 - Vasculitis Flashcards
small vessel vasculitides x4
HSP / IgA vasculitis
eosinophilic GPA
GPA
microscopic polyangitis
medium vessel vasculitides x 3
polyartertis nodosa
eosinophilic GPA
Kawasaki disease
large vessel vasculitides x2
giant cell arteritis
Takayasu’s arteritis
generic features of all vasculitis
purpura - non blanching small purple lesions joint/muscle pain peripheral neuropathy renal impairment GI disturbance anterior uveitis HTN FLAWS
testing for vasculitis
CRP + ESR
ANCA antibodies
p ANCA antibodies
microscopic polyangitis
eosinophilic GPA
c ANCA
GPA
granulomatosis with polyangitis
IgA vasculitis
aka Henoch Shonlein purpura
under 10 yrs old
buttock + leg rash
triggered by URTI
purpura
joint pain
abdo pain
renal impairment
recover in 4-6 weeks with supportive care
eosinophilic granulomatosis with polyangitis
aka Churg Strauss
high eosinophils
lung + skin probs (can present as severe asthma)
microscopic polyangitis
renal failure
can have lung features
granulomatosis with polyangitis
nose bleeds
crusty nose secretions
hearing loss
sinusitis
saddle shaped nose
cough + haemoptysis
glomerulonephritis
polyarteritis nodosa
assoc with hep B
livedo reticularis
Kawasaki disease
under 5 years old
fever 5+ days long rash bilat conjunctivitis skin peeling strawberry tongue
treat - aspirin + IVIG
can get coronary artery aneurysms
Takayasu’s arteritis
affects aorta
‘pulseless disease’
under 40 yrs old
claudication, syncope
