Haematology 8 - Lymphoma

Question 1

Hodgkin’s lymphoma and risk factors

Answer 1

1 in 5 lymphomas

HIV
EBV
autoimmune conditions
FH

Question 2

presenting features of

Hodgkin’s lymphoma

Answer 2

enlarged LN (neck, axilla, inguinal)

non tender + rubbery
may be painful when they drink alcohol

FLAWS B symptoms
SOB, infections, pain

Question 3

investigations for lymphoma

Answer 3

LDH
lymph node biopsy

CT,MRI,PET staging

Question 4

key cell seen on biopsy in Hodgkins

Answer 4

Reed Sternberg cells (owl eye inclusions)

Question 5

Ann Arbor staging 1-4

Answer 5

1 - 1 area only
2 - 2 on this side of diaphr
3 - 2 on one side, 1+ on the other
4 - widespread + mets

for lymphoma staging

Question 6

non Hodgkin lymphoma

Answer 6

many many types

Burkitt - EBV, HIV, malaria associated
MALT - H pylori infection
diffuse large B cell lymphoma - ‘rapidly growing painless mass inn over 65s’