Renal 5 - Glomerulonephritis Flashcards
define nephritis
simply means kidney inflammation
not a condition
define nephritic syndrome
key is protein but <3g /24hr
haematuria
oliguria (significant)
fluid retained
define nephrotic syndrome
protein >3g/24hr
peripheral oedema
serum albumin <25
high cholesterol
define interstitial nephritis
inflammation is between the cells and the tubules (i.e. the interstitium)
define glomerulosclerosis
scarring of glomerulus tissue
general glomerulonephritis treatment
supportive +/-
steroids +/-
anti HTN meds
most common causes of nephrotic syndrome in adults and kids
kids - minimal change (give steroids)
adults - focal segmental glomerulosclerosis
IGA nephropathy
most common primary GN
peaks in 20s
IgA deposits + glomerular mesangial proliferation
days after URTI
membranous glomerulonephritis
most common overall
IgG and complement deposits on the basement membrane
post strep glomerulonephritis
typical under 30
weeks after strep infection
nephritic
can be called ‘diffuse proliferative GN’
goodpasture syndrome
anti GBM antibodies
GN + haemoptysis
rapidly progressive GN
crescenteric glomerulonephritis
usually very acute and can be secondary to Goodpasture
