Infectious Diseases 14 - Malaria Flashcards

1
Q

summarise malaria cause

A

Anopheles mosquitoes

P falciparum (worst and most common)
vivax ovale malariae
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2
Q

life cycle of malaria

A
night time bitten 
sporozoites in gut of mosquito
travel to human liver
(hypnozoites dormant if viv or oval)
mature and infect RBCs
48 hours later, pop!
haemolytic anaemia
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3
Q

presentation of malaria

A

high risk country 1-4 weeks ago

FLAWS, flu prodrome 
anaemia
hepatomegaly
splenomegaly
jaundice
48 hrly fevers
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4
Q

diagnosing malaria

A

thin thick blood film

3 samples over 3 days

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5
Q

managing severe malaria

A
  1. artesunate

2. quinine

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6
Q

complications of falciparum malaria

A
seizures
AKI
pulmonary oedema
DIC
death
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7
Q

malaria prophylaxis

A

malarone daily 2 days before and 1 week after

use nets + DEET
know signs
be aware

(doxy cheaper but gives sun rash, mefloquine can cause bad dreams + psych SEs)

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