Infectious Diseases 14 - Malaria Flashcards
1
Q
summarise malaria cause
A
Anopheles mosquitoes
P falciparum (worst and most common) vivax ovale malariae
2
Q
life cycle of malaria
A
night time bitten sporozoites in gut of mosquito travel to human liver (hypnozoites dormant if viv or oval) mature and infect RBCs 48 hours later, pop! haemolytic anaemia
3
Q
presentation of malaria
A
high risk country 1-4 weeks ago
FLAWS, flu prodrome anaemia hepatomegaly splenomegaly jaundice 48 hrly fevers
4
Q
diagnosing malaria
A
thin thick blood film
3 samples over 3 days
5
Q
managing severe malaria
A
- artesunate
2. quinine
6
Q
complications of falciparum malaria
A
seizures AKI pulmonary oedema DIC death
7
Q
malaria prophylaxis
A
malarone daily 2 days before and 1 week after
use nets + DEET
know signs
be aware
(doxy cheaper but gives sun rash, mefloquine can cause bad dreams + psych SEs)