Revise Radiology Neuro 4 Flashcards
Putaminal atrophy with hyperintense T2 rim
Multi-system atrophy
TB pachymeningitis involves
Middle cranial fossa, cavernous sinus, tentorium
Leigh disease distribution
Spares mamillary bodies
Boston CAA Criteria tiers
Definite, Probable with supporting features, Probable, Possible
Astrocytoma imaging featue
Patchy enhancement.
Haemorrhage is rare.
Immunosuppressed, PML cause
JC virus (polyoma virus)
Pilocytic astrocytomas associated with
NF1
Astrocytoma histology
Rosenthal fibres
Most sensitive MRI sequence for SAH
FLAIR
Genetic mutation associated with Pineoblastoma
DICER-1
Low T2, enhancing lesions in posterior fossa
Erdheim Chester disease
Most common syndrome associated with megalencephaly
NF-1
Dilated, non-enhancing perivascular spaces. B/L low T1/T2, ring enhancing lesions
Cryptococcus
Underlying mechanism of spinal AVF
Venous hypertension reducing tissue perfusion
Band heterotopia/double cord syndrome responsible chromosome
Chromosome X
Metastatic melanoma histology
Pleomorphic cells with prominent nucleoli
Slit like ventricles
Intracranial hypertension
Meningioma vs Craniopharyngioma
Meningioma can displace the diaphragm sellae superiorly
Dural AVF classification system
Cognard classification
T2 bright, non-enhancing brainstem lesion, flattened 4th ventricle
Diffuse Pontine Glioma
HTN, headaches, seizures. Parietal and occipital white matter oedema
PRES
Metachromic Leukodystrophy responsible enzyme deficiency
Arylsulphatase A
Type III AVM Rx
Embolisation and surgical resection
Most specific signs of IIH
Intraoccular protrusion of optic nerve head, flattened posterior sclera, Transverse sinus stenosis
Untreated Wernicke’s mortality
20%
Transverse, single lobed cerebellum with absent vermis
Rhombencephalosynapsis
Most common location for spinal ependymomas
Cervical spine (44%)
Megalencephaly associated with
Polymicrogyria and agyria
Fisher SAH grading system
0 = No SAH. 1 = Focal or thin (<5mm) diffuse with no IVH (24% chance of symptomatic vasospasm).
2 = Focal or thin diffuse with IVH (33% chance of symptomatic vasospasm).
3 = Thick SAH, no IVH, 33% chance of symptomatic vasospasm
4 = Thick SAH with IVH, 40% chance of symptomatic vasospasm
?CVST, bilateral thalamic oedema on CT, next Ix
MR Venogram
Homogenously enhancing pineal mass with central calcification
Germinoma
Perfusion feature of high grade glioma
High cerebral blood volume
Genetic condition associated with multiple spinal AVMs
Osler-Weber-Rendu
Meckel-Gruber syndrome triad
Occipital encephalocele, multiple renal cysts, polydactyly
Kernohan’s phenomenon
Transtentorial herniation leads to compression of contralateral cerebral peduncle which causes ipsilateral motor defects
Cortical thickening, focal signal abnormality from cortex to ventricle
Focal Cortical Dysplasia type IIb
T2 hyperintense lesions with perivascular enhancement in HIV
Epstein Barr Virus
Ix for limbic encephalitis
MR Spectroscopy
Ix to exclude Alzeimers
Amyloid PET
Down’s associated with
Cerebral Amyloid Angiopathy
Pachymeningeal enhancement & Brainstem sagging
Spontaneous intracranial hypotension
Bilateral T2 intense lesions with ring enhancement and haemorrhage
Acute haemorrhagic Encephalomyelitis
Gold standard Ix for Spinal AVF
Catheter Angio
?ICA dissection best Ix
DSA
Older patients with AVMs more likely to
Haemorrhage
Loss of transverse fibres in pons
Hot Cross Bun Sign - Multi system atrophy
Commonest complication of type 2 Spinal AVM
SAH
Well defined, heterogenous spinal signal abnormality with T2 hypointense rim
Spinal cavernous malformation
Hydrocephalus associated with subfalcine herniation (side)
Contralateral
Achondroplasia causes
Communicating hydrocephalus
Focal Cortical Dysplasia presenting in adults
Type 1
Leptomeningeal tumour spread most associated with (WHO Grade)
Grade IV
Spinal PNET hystology
Small round blue cells
Most sensitive sequence for CJD
DWI
ASPECT score for mechanical thrombectomy
> 7
Osmotic demyelination syndrome distribution
Spares corticospinal tracts
Cystic lesions with oedema and enhancement
Colloid Neurocysticercosis
Potts tumour Ix
MRI with contrast
Thickened infundibulum & Loss of posterior bright spot
HPA axis sarcoidosis
Descent of tonsils and brainstem
Chiari 1.5
Dural based tumour with skull invasion
Haemangiopericytoma