Pregnancy And Diabetes Flashcards

1
Q

Gestational diabetes?

A

Diabetes or impaired glucose: fasting glucose equal or more 5.6

2 hour GTT glucose over or equal 7.8

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2
Q

In early pregnancy, facilitated anabolism?

A

Increased insulin sensitivity

And lower glucose conc, increased maternal energy stores

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3
Q

In later pregnancy facilitated catabolism?

A

Increased insulin resistance and increased transplacental passage of nutrients so rapid fetal growth

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4
Q

Abnormal placental programming?

A

Increased risk of pre eclampsia and excessive glucose transport

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5
Q

Diabetes control in 1st semester treatment?

A

Insulin regimen, lifestyle modification, folic acid 5mg/day, glucose monitoring

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6
Q

Shoulder dystocia?

A

Shoulder gets stuck

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7
Q

How many women at antenatal booking is obese?

A

1 in 5

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8
Q

Treatment of hyperglycaemia?

A

Glucose monitoring, finger prick tests, fasting 1 hour
Freestyle libre
Nutrition and exercise
Ultrasound fetal abdominal girth monthly from 28 weeks
Mother’s to observe fetal movements

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9
Q

Targets for hyperglycamia?

A

1 hour postprandial less than 7
Fasting less than 5.1
Fetal abdominal girth less than 70th centile

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10
Q

Gestational diabetes treatment?

A

Metformin
Basal insulin
Basal bolus insulin
Glibenclamide

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11
Q

What is gestational diabetes?

A

Any abnormal glucose tolerance presenting after 1st trimester of pregnancy

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12
Q

1st semester malformations?

A
Single ventricle and sacral dysgeisnesis
Hydrocephalus
Meningomyocele
Central cyanosis
Renal agenesis
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13
Q

Risk factors of IGT and diabetes?

A

PCOS
Fam history of type 2
Obesity
Previous gestational diabetes

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14
Q

Problems with macrosomia?

A
Difficult birth
Shoulder dystocia
Breathing problems
Jaundice
Hypoglycaemia
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15
Q

Increased perinatal mortality?

A

Type 2 x9

Type 1 x4

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16
Q

Screening for GD?

A
Obesity over 30
PCOS
Obesity
Fam his
High risk racial
Previous GD
Older age at booking

Then test at 26-28 weeks

17
Q

Drug treatment for prepregnancy and 1st trimester hyperglycaamia?

A

Basal bolus regimen

18
Q

Breastfeeding reduces diabetes in children?

A

30-50% of risk

Prolonged exclusive 67%

19
Q

Post partum GDM managment

A

Antibody status
Screen diabetes 12 weeks hba1c and fasting glucose
Advice
Annual glucose screening

20
Q

What percent of women with gd get type 2 at 10 years?

A

50%

21
Q

What is the definition of gestational diabetes?

A

Any newly found abnormal glucose tolerance tests after the 1st trimester of pregnancy

22
Q

First trimester problems?

A
Hydrocephalus
Menoingomyelocoele
Central cyanosis in CHD
Single ventricle and sacral dysgenesis
Renal agenesis
23
Q

What should you check for in women in terms of risk factors with unknown cases of diabetes/IGT?

A
Previous gestational diabetes
Fam history
Obesity 
PCOS
High risk racial group
24
Q

What are the problems with macrosomia?

A
Difficult birth
Shoulder dystocia 
Breathing problems
Jaundice
Hypoglycaemia
25
Q

Contraception and diabetes?

A

Progestagen only pill
Combined OCP ( low dose) after 6 weeks
Mirena Intrauterine system
Sterilisation / Vasectomy

26
Q

You should give pregnant woman in first trimester?

A

Folic acid 5mg

Aspirin 150 mg/day