Physiology Of Pregnancy Flashcards

1
Q

Amniotic fluid in second semester?

A

For fetal urine

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2
Q

Which hormone is released from corpus luteum then by placenta?

A

HCG- peaks in first days to weeks, double in number every 24 hours

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3
Q

Spike of HCG at what week?

A

9week mark

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4
Q

Progesterone maintains what?

A

Quiescence, not allowing contraction

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5
Q

What is HCG created by?

A

Trophoblast

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6
Q

What alters maternal carbohydrate and lipid metabolism to provide steady state of glucose for feotus?

A

Human placental lactogen

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7
Q

What induces maternal insulin resistance?

A

Human placental gonadotrophin

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8
Q

Alpha unit of HCG mimics what?

A

FSH, LH, TSH

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9
Q

High HCG may indicate?

A

Multiple preganancy or molar preganancy

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10
Q

For pregnancy testing what do we check for?

A

Beta unit of HCG

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11
Q

Problem of progestrone smooth muscle relaxtation?

A

Laxity in ligaments of pelvis, supra-pubic dysfunction, gastric reflux and constipation, lobule-alveolar development in breasts

May need crutches, a belt or exercises

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12
Q

What is progesterone responsible for in breasts?

A

Lobulo alveolar development

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13
Q

Plasma volume increase?

A

40% from 2.5l to 3.7l

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14
Q

Red blood cell increase by what percent?

A

25%, leads to dilutional anaemia

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15
Q

Whta happens to colloid osmotic pressure?

A

Falls, causing shift of fluid into extracellular fluid, fluid in hands and feet

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16
Q

Womans Heart enlarges by how much?

17
Q

Innocent systolic murmurs are common at what percent?

18
Q

Preipheral resistance decreases by?

A

35%, peripheral vasodilatation due to progesterone

19
Q

What happens to respiratory in pregnancy?

A

Resp rate increases, bronchodilation, rib cage increases, change in tidal volume

20
Q

What is causing palpitations?

A

Increase HR

21
Q

Pre-eclampsia causes?

A

Significant odema, swelling in face

22
Q

Renal flow is increased by?

A

50%, kidney length by 1cm increased

23
Q

Levels of thyroid changes?

A

Increase in T3/T4, thyroid binding globulin due to oestrogen

24
Q

What happens to bhcg in pregnancy?

A

Dramatic rise in first days-weeks, released by corpus luteum then by placenta.

25
Oestrogen is responsible for?
Breast growth Aerolar enlargement
26
High levels of hcg can cause?
Hyperemesis
27
Oestrogen stimulates?
Prolactin synthesis
28
Clotting factors increase in pregnancy, which ones?
Plasma fibrinogen, platelets, factor 8 and Von willebrand factor
29
Diastolic murmurs suggest?
Cardiomyopathy
30
Musculoskeletal changes?
``` Lumbar lordosis Ligamentous laxity- pelvic girdle pain Stretch marks Skin pigmentation- linea nigra, melasma, dark nipples Carpal tunnel, due to increased oedema Sciatica Cramps ```
31
Progesterone is responsible for?
Breast lobule enlargement
32
Creatinine and urea?
Decrease in pregnancy