Ovarian Cysts

Question 1

What does stroma do?

Answer 1

Produces hormone

Question 2

Where can tumours arise?

Answer 2

Germinal epithelium

Question 3

From where can cysts develop?

Answer 3

In follicles and corpus luteum

Question 4

How many women have a cyst?

Answer 4

10%

Question 5

What percent of cysts are benign?

Answer 5

90%

Question 6

Tumour markers?

Answer 6

Beta hcg
Alpha fetoprotein
Ldh (lactate dehydrogenase)

Question 7

Which stromal tumour is most common?

Answer 7

Granulosa tumour -looks gelatinous yellow pus like

Has sertoli leydig tumour

Question 8

Borderline tumour is not ?

Answer 8

Cancer and can not spread to other organs

Question 9

Which marker is used to differenitate between benign and cancer?

Answer 9

CA 125 really high- malignant

But can go up with many things

Question 10

Risk of malignancy index?

Answer 10

Menstrual x usss x CA125

Question 11

What present of women present at advances stage of ovarian cancer?

Answer 11

60-80%

Question 12

Treatment for ovarian cancer?

Answer 12

bevacizumab (targeting VEGF, chemotherapy (carboplatin +/-taxol), surgery

Question 13

What type of cysts are there?

Answer 13

Follicular cyst and luteal cyst

Question 14

What percent of all women in UK will be admitted by age of 65 with an ovarian cyst?

Answer 14

4

Question 15

What percent of cyst are malignant, surgically managed?

Answer 15

13% in premenopausal and 45% in post menopausal

Question 16

Symptoms of ovarian cysts?

Answer 16

Asymptomatic
Pain
Menstrual disruption
Pressure

Question 17

What length would you allow before reacting?

Answer 17

For premenopausal women- 8cm

Post menopausal- 5cm

Question 18

Complexity of cyst on ultrasound?

Answer 18

Solid
Septae
Bilateral
Free fluid

Question 19

Gravado 0 Parus 0?

Answer 19

No pregnancies no babies

Question 20

What can happen after rupture of ovarian cyst?

Answer 20

Peritonitis, but if its mucus cyst the pseudomyxoma peritonei

Question 21

What does haemorrhage into a cyst look like on an ultrasound?

Answer 21

Bad tv service, mostly in a specific region

Question 22

Blood supply for ovary comes from?

Answer 22

Renal vessels

Question 23

Which cells do dermoid cyst come from?

Answer 23

Germ cells

Question 24

If you get a cancer in germ cell normally happens what age women?

Answer 24

Under 30

Question 25

2 or more relative first degree, risk can go up to?

Answer 25

50%

Question 26

Stromal tumour types?

Answer 26

Most common- granulosa cell

Sertoli-leydig

Question 27

How to treat ovarian masses?

Answer 27

Chemo- carboplatin and taxol

Bevacizumab , targets a cancer cell vascular endothelial growth factor