Multiple Twin Pregnancies Flashcards

1
Q

Incidence of multiple births in europe?

A

9-20 per 1000 deliveries

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2
Q

In 1978?

A

First test tube baby, IVF

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3
Q

In 2002 the law said?

A

Forbidding putting back more than one embryo in IVF

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4
Q

Causes of multiple pregnancy?

A
Fertility treatment
Maternal age
Increase parity
Family history 
Ethnicity 

All due to super ovulation

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5
Q

Zygosity?

A

How many zygotes did pregnancy come from?

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6
Q

Chorionicity?

A

How many placentas you’ve got?

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7
Q

Monozygotic accounts for how much of twins?

A

1/3

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8
Q

Dizygous accounts for what of twin pregnancy?

A

2/3

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9
Q

What fraction of monozygous twins are dichorionic?

A

1:3

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10
Q

Loss rate in monochorionic monozygous twins?

A

X3

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11
Q

Diagnosis of twin pregnancy?

A

Uterine size

Ultrasound

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12
Q

What percentage of deliveries of twins are found at birth?

A

50%

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13
Q

To identify two chorions look for?

A

Lambda sign

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14
Q

Monochorionic split at what stage?

A

Blastocyst

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15
Q

Which pregnancy is high risk?

A

Monoamniotic

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16
Q

How to tell if diagnostic or mono?

A

Small thin membrane in between if diamniotic

17
Q

Multiple pregnancy complications?

A
Symptoms of pregnancy
Anaemia
Hypertension
Intrauterine growth restriction 
Pre term labour 
Delivery problems
Perinatal mortality
18
Q

Stillbirth happens at?

A

After 24 weeks

19
Q

Early neonatal death happens?

A

First 7 days

20
Q

Neonatal death?

A

First 28 days

21
Q

Perinatal death?

A

Stillbirth and early neonatal

22
Q

First trimester management?

A

By 14 week determine chorionicity

Screening for chromosomal anomalies

Discuss fetal reduction

23
Q

Second trimester management?

A

Fetal abnormality detection

Serial growth scans, DC
monthly from 24 weeks

MC- twin to twin transfusion, abnormal anastomoses, scan every 2 weeks from 16-24 then monthly

Maternal complications

24
Q

Monochorionic twins problems?

A

More fetal malformation, fetal growth restriction and twin twin transfusion

25
How to deal with twin twin transfusion?
Laser, in utero, destroying blood vessels Amnio reduction Early delivery by caesarean
26
Third semester management?
Monitor bp Delivery planning Pre term labour Scanning
27
Delivery planning?
DC- 37 weeks and 6 days If twin 1 is not head down, then c section recommended MC- 37 weeks All by c section historically, patient preference