Multiple Twin Pregnancies Flashcards
Incidence of multiple births in europe?
9-20 per 1000 deliveries
In 1978?
First test tube baby, IVF
In 2002 the law said?
Forbidding putting back more than one embryo in IVF
Causes of multiple pregnancy?
Fertility treatment Maternal age Increase parity Family history Ethnicity
All due to super ovulation
Zygosity?
How many zygotes did pregnancy come from?
Chorionicity?
How many placentas you’ve got?
Monozygotic accounts for how much of twins?
1/3
Dizygous accounts for what of twin pregnancy?
2/3
What fraction of monozygous twins are dichorionic?
1:3
Loss rate in monochorionic monozygous twins?
X3
Diagnosis of twin pregnancy?
Uterine size
Ultrasound
What percentage of deliveries of twins are found at birth?
50%
To identify two chorions look for?
Lambda sign
Monochorionic split at what stage?
Blastocyst
Which pregnancy is high risk?
Monoamniotic
How to tell if diagnostic or mono?
Small thin membrane in between if diamniotic
Multiple pregnancy complications?
Symptoms of pregnancy Anaemia Hypertension Intrauterine growth restriction Pre term labour Delivery problems Perinatal mortality
Stillbirth happens at?
After 24 weeks
Early neonatal death happens?
First 7 days
Neonatal death?
First 28 days
Perinatal death?
Stillbirth and early neonatal
First trimester management?
By 14 week determine chorionicity
Screening for chromosomal anomalies
Discuss fetal reduction
Second trimester management?
Fetal abnormality detection
Serial growth scans, DC
monthly from 24 weeks
MC- twin to twin transfusion, abnormal anastomoses, scan every 2 weeks from 16-24 then monthly
Maternal complications
Monochorionic twins problems?
More fetal malformation, fetal growth restriction and twin twin transfusion