Multiple Twin Pregnancies Flashcards

1
Q

Incidence of multiple births in europe?

A

9-20 per 1000 deliveries

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2
Q

In 1978?

A

First test tube baby, IVF

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3
Q

In 2002 the law said?

A

Forbidding putting back more than one embryo in IVF

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4
Q

Causes of multiple pregnancy?

A
Fertility treatment
Maternal age
Increase parity
Family history 
Ethnicity 

All due to super ovulation

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5
Q

Zygosity?

A

How many zygotes did pregnancy come from?

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6
Q

Chorionicity?

A

How many placentas you’ve got?

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7
Q

Monozygotic accounts for how much of twins?

A

1/3

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8
Q

Dizygous accounts for what of twin pregnancy?

A

2/3

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9
Q

What fraction of monozygous twins are dichorionic?

A

1:3

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10
Q

Loss rate in monochorionic monozygous twins?

A

X3

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11
Q

Diagnosis of twin pregnancy?

A

Uterine size

Ultrasound

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12
Q

What percentage of deliveries of twins are found at birth?

A

50%

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13
Q

To identify two chorions look for?

A

Lambda sign

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14
Q

Monochorionic split at what stage?

A

Blastocyst

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15
Q

Which pregnancy is high risk?

A

Monoamniotic

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16
Q

How to tell if diagnostic or mono?

A

Small thin membrane in between if diamniotic

17
Q

Multiple pregnancy complications?

A
Symptoms of pregnancy
Anaemia
Hypertension
Intrauterine growth restriction 
Pre term labour 
Delivery problems
Perinatal mortality
18
Q

Stillbirth happens at?

A

After 24 weeks

19
Q

Early neonatal death happens?

A

First 7 days

20
Q

Neonatal death?

A

First 28 days

21
Q

Perinatal death?

A

Stillbirth and early neonatal

22
Q

First trimester management?

A

By 14 week determine chorionicity

Screening for chromosomal anomalies

Discuss fetal reduction

23
Q

Second trimester management?

A

Fetal abnormality detection

Serial growth scans, DC
monthly from 24 weeks

MC- twin to twin transfusion, abnormal anastomoses, scan every 2 weeks from 16-24 then monthly

Maternal complications

24
Q

Monochorionic twins problems?

A

More fetal malformation, fetal growth restriction and twin twin transfusion

25
Q

How to deal with twin twin transfusion?

A

Laser, in utero, destroying blood vessels

Amnio reduction

Early delivery by caesarean

26
Q

Third semester management?

A

Monitor bp
Delivery planning
Pre term labour
Scanning

27
Q

Delivery planning?

A

DC- 37 weeks and 6 days
If twin 1 is not head down, then c section recommended

MC- 37 weeks
All by c section historically, patient preference