Physiology Of Puberty Flashcards
Thelarche?
Breast development
Nocturnal pulsatilla GnRH release every?
90 to 120 mins from 6 to 9 years
Mean weight at menarche?
47.8kg
ACTH stimulates what?
Zona reticularis in adrenal cortex
For boys testicular volume of more than4 after what age?
9
Breast growth for girls happens after what age?
8
Which hormone acts on growth plates?
Oestrogen
Hamartoma?
Benign tumour in head, cause puberty and gelastic seizures (laughing fits)
FSH control on?
sertoli cells
LH control on?
leydig cells , production of testosterone
Production of testosterone happens?
95% from testes and 5% from adrenals
What is testosterone converted to?
DHT in cells
Age of menarche affected by Body % fat?
16-24
Types of precocious puberty?
Central (true), Peripheral pseudo
How to treat precocious puberty?
long acting LHRH analog therapy, cessation of gonadotrophin release
congenital adrenal hyperplasia?
more cholesterol making testosterone
treatment for lack of aldosterone?
fludrocortisone
treatment of lack of cortisol?
hydrocortisone
kleinfelter prevalence?
1 in 1000
symptoms of Kleinfelters?
androgen deficiency, behavioural problems, azoospermia, infertility, microgenitalia
treatment for kelinfelters?
lifelong testosterone replacement therapy
turner syndrome prevalence?
1 in 2000
turners symptoms?
short stature, streak gonads, primary amenorrhoea
WEBBING OF NECK, CUBITUS VALGUS
coarction of aorta, horse shoe kidneys
lymphedema
help for turners?
growth hormone therapy, ongoing hrt, assisted conception