Physiology Of Puberty Flashcards

1
Q

Thelarche?

A

Breast development

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2
Q

Nocturnal pulsatilla GnRH release every?

A

90 to 120 mins from 6 to 9 years

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3
Q

Mean weight at menarche?

A

47.8kg

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4
Q

ACTH stimulates what?

A

Zona reticularis in adrenal cortex

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5
Q

For boys testicular volume of more than4 after what age?

A

9

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6
Q

Breast growth for girls happens after what age?

A

8

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7
Q

Which hormone acts on growth plates?

A

Oestrogen

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8
Q

Hamartoma?

A

Benign tumour in head, cause puberty and gelastic seizures (laughing fits)

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9
Q

FSH control on?

A

sertoli cells

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10
Q

LH control on?

A

leydig cells , production of testosterone

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11
Q

Production of testosterone happens?

A

95% from testes and 5% from adrenals

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12
Q

What is testosterone converted to?

A

DHT in cells

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13
Q

Age of menarche affected by Body % fat?

A

16-24

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14
Q

Types of precocious puberty?

A

Central (true), Peripheral pseudo

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15
Q

How to treat precocious puberty?

A

long acting LHRH analog therapy, cessation of gonadotrophin release

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16
Q

congenital adrenal hyperplasia?

A

more cholesterol making testosterone

17
Q

treatment for lack of aldosterone?

A

fludrocortisone

18
Q

treatment of lack of cortisol?

A

hydrocortisone

19
Q

kleinfelter prevalence?

A

1 in 1000

20
Q

symptoms of Kleinfelters?

A

androgen deficiency, behavioural problems, azoospermia, infertility, microgenitalia

21
Q

treatment for kelinfelters?

A

lifelong testosterone replacement therapy

22
Q

turner syndrome prevalence?

A

1 in 2000

23
Q

turners symptoms?

A

short stature, streak gonads, primary amenorrhoea

WEBBING OF NECK, CUBITUS VALGUS

coarction of aorta, horse shoe kidneys

lymphedema

24
Q

help for turners?

A

growth hormone therapy, ongoing hrt, assisted conception

25
Q

gonadotrophin deficiency can be caused by?

A

kallman, cant smell

26
Q

In 25% of females first pubertal sign is ?

A

Pubarche

27
Q

DHEAS and androstenedione begins in girls and boys at?

A

Girls- 6

Boys-8

28
Q

What is the definition of puberty?

A

The stage of physical maturation in which an individual becomes physiologically capable of pro-creation (sexual reproduction

29
Q

When does a growth spurt happen in girls?

A

8 to 14

30
Q

When does menarche happen?

A

10 to 16 years

31
Q

How many girls reach menarche in primary school?

A

1 in 8

32
Q

Early or precocious puberty is?

A

Girls under 8

Boys under 9

33
Q

Delayed puberty is?

A

Over 14 for both

34
Q

How to treat someone with gonadotrophin deficiency?

A

Lifelong testosterone replacement therapy