Pelvis 03: Female Reproductive System Flashcards
What does the female reproductive tract consist of?
Vulva, vagina, cervix, uterus, uterine tubes, ovaries
What are the intraperitoneal structures of the female reproductive system?
Ovaries, uterine tubes, fundus of the uterus, most of the body of the uterus
What are the subperitoneal structures of the female reproductive system?
Lower uterus, cervix, vagina; the exception is the posterior fornix
What are the three endopelvic fascia ligaments that suspend and support the female reproductive tract?
Pubocervical ligament, transverse cervical ligament, uretosacral ligament
Round ligament of the uterus
A ligament in females that is analogous to the male spermatic cord; it runs from the uterus superiorly, and then inferiorly through the deep and superficial inguinal rings; it goes to the labia majora
Ligament of the ovary
A ligament that runs between the uterus and the ovary
What is the remnant structure that becomes the round ligament of the uterus and the ligament of the ovary?
Gubernaculum
Broad ligament
A ligament consisting of peritoneum and parametrium that drapes over the pelvic organs
What are the three parts of the broad ligament
Mesovarium, mesosalpinx, mesometrium
Mesovarium
Part of the broad ligament that suspends the ovaries
Mesosalpinx
Part of the broad ligament that suspends the uterine tubes
Mesometrium
Part of the broad ligament between the junction of mesovarium+mesosalpinx and the parietal peritoneum
Parametrium
Tissue enclosed by the broad ligament beside the uterus
Perimetrium
Tissue that lies around the uterus
hysterectomy
An operation to remove the uterus from the body
What are the three places where the ureter is in danger during hysterectomy
1) Distal ureter where it is crossed by the uterine artery
2) Dorsal to the suspensory ligament of the ovary at the pelvic brim
3) intramural portion of the ureter at the level of the fornices
Ovaries
Paired organs that are the site of ova production
Oogenesis
The process of forming ova
Secretory properties of the ovary
An endocrine organ; it secretes estrogen and progesterone
What are the four histological components of the ovary?
Visceral peritoneum, stroma, follicles with granulosa cells, germ cells
Germinal epithelium
The visceral peritoneum of the ovaries
What is the cell type of the germinal epithelium
Simple squamous to cuboidal mesothelium
Ovarian stromal cells
Cells of the stroma of the ovary that synthesize hormones and form theca
Theca
Muscle-like tissue that surrounds the developing follicle in the ovary
Primordial germ cells
The primitive germ cells, before male/female differentiation occurs
What are the stages of the development of female ovaries
Week 3: PGCs develop at posterior end of primitive streak
Week 4: PGCs migrate into endoderm of yolk sac
Week 5: PGCs migrate into genital ridge of intermediate mesoderm
Week 6: PGCs enter the developing gonad
Primordial follicle
A follicle encasing a primary oocyte that is surrounded by squamous epithelium
Primary follicle
A follicle encasing a primary oocyte that is surrounded by cuboidal epithelium
What marks the transition of a primordial follicle to a primary follicle?
The epithelium changes from sqamous to cuboidal under the influence of FSH
What stage of meiosis is the primary oocyte arrested in in the primary follicle?
Meiosis 1
Granulosa cells
The cells of the follicular epithelium that surround the primary (not primordial) follicle
Pre-antral follicle
A follicle that is defined by multiple layers of granulosum and thecal cells; there is no antrum
Antral follicle
Also known as secondary follicle; there is large antrum; culumnus oophorus at one end is continuous with the stratum granulosum
What cells of the follicle produce estrogen and progesterone?
Theca interna
Follicular antrum
A cavity in a follicle that contains fluid
Graafian Follicle
Also known as tertiary follicle; marked by a very large antrum and a more developed culumnus oophorus
Culumus oophorus
Granulosum + oocyte inside a follicle
Uterine tube
A tube that connects the uterine cavity to the peritoneal cavity and transports ova to the uterine cavity
Plicae of the uterine tube
Folds consisting of epothelium and supporting tissue; there are smooth muscles within them to allow movement
What are the cell types found in the utering tube plicae?
Ciliated; nonciliated; intercalated. All are simple columnar
Nonciliated epithelium of the uterine tube plicae
Secretory cells; they secrete fluid that transports and nourishes gametes and capacitates sperm
Ciliated epithelium of the uterine tube plicae
Generate the fluid flow
Tubal ligation
The cutting of the fallopian tube to prevent fertilization
Uterine fundus
The top part of the body of the uterus
What are the two divisions of the cervis?
Vaginal (invaginates into the vagina) and supravaginal (still inside the uterus)
From outside to inside, what are the sections of the uterus, cervix, and vagina?
Introitus, vaginal canal, vaginal vault, external os, cervix canal, internal os, uterine cavity
Vaginal canal
The narrower part of the vagina
Vaginal vault
The wider part of the vagina, where the cervix opens into
External os
The external opening of the cervix; opens into the vagina
Cervial canal
The canal of the cervix
Internal os
The internal opening of the cervix; opens into the uterine cavity
Introitus
The opening of the vagina into the outside world
Angle of anteversion
The angle between the cervix and the vagina
Anteverted uterus
A uterus that is tipped anterioraly relative to the angle of anteversion
Retroverted uterus
A uterus that is not tipped anteriorally relative to the angle of anteversion
Angle of anteflexion
The angle between the cervix and the body of the uterus
Anteflexed uterus
A uterus that is bent anteriorally relative to the angle of anteflexion
Retroflexed uterus
A uterus that is not bent anteriorally relative to the angle of anteflexion
What are the three layers of the uterus?
Perimetrium -> myometrium -> endometrium
Perimetrium
The outer layer of the uterus’ consists of peritonium and adventitia
Myometrium
The middle layer of the uterus; has a middle muscular layer that is used for contractions during labor and menstruation
Endometrium
The inner layer of the uterus; the inner mucosa. Shed during menstruation
What are the three phases of the uterine mentrual cycle?
Proliferative phase -> secretory phase -> menstrual phase
Proliferative phase of the uterine menstrual cycle
Induced by estrogen and progesterone; preapres the endometrium for implantation
Secretory phase of the uterine menstrual cycle
Induced by the secretion of progesterone from the corpus luteum; induces glycogen-rich secretions from endometrial glands
Menstural phase of the uterine menstrual cycle
Induced by the death of corpus luteum (thus, the lack of progesterone) and no implantation. Shedding of the layers of the endometrium
What are the layers of the endometrium?
Stratum functionalis and stratum basalis
Stratum functionalis
The inner layer of the endometrium that is shed during menstruation; divided into stratum compactum (deeper) and stratum spongiosum
Stratum compactum
The deeper layer of the stratum functionalis
Stratum spongiosum
The more superficial layer of the stratum functionalis
Stratum basalis
The outer layer of the endometrium; it is not shed during menstruation and acts as a regenerator for stratum functionalis
What is the blood supply of the endometrium?
Uterine artery -> arcuate artery -> radial arteries -> spiral arteries
Spiral arteries
Arteries that supply the endometrium; they are spiral so that they can expand in the case of implantation and growth of the fetus
Endometriosis
Ectopic endometrial tissue outside of the uterus
Retrograde menstruation
Where menses backfills into the peritoneal cavity
What epithelium lines the cervical canal?
Simple columnar
What epithelium lines the vaginal end of the cervix?
Stratified squamous
Lateral fornices
Bending of the vagina at the two lateral sides around the external os of the cervix; there is an anterior and posteror fornix
What are the smooth muscle layers of the vagina?
Inner circular and outer longitudinal
What is the adventitia of the vagina?
It fuses with the adventitia of the bladder and urethra anteriorally; it fuses with the adventitia of the rectum posteriorly
How does the uterus change with pregnancy?
Its mass increases from 50g to 1.1 kg, and its volume increases from 12ml to 9.5L
How does the cervix change at labor onset?
It softens, effaces (thins out), dilates, and loses its mucus plug
Stage 1 of labor?
Begins at the onset of labor and ends when the cervix is completed thinned and dilated
Stage 2 of labor
Ends with the birth of the baby
Stage 3 of labor
Ends with the birth of the placenta
Stage 4 of labor
Last two hours after the birth of the placenta