Body Plan 11: Skin and Joints Flashcards
Skin
Largest organ of the body
What separates the epidermis and dermis?
Basement membrane
Rete Ridges
Epidermal ridges that dip into the dermis
Dermal papillae
Dermal ridges that pop up into the epidermis
Epidermal cells
Mostly keratinocytes arising from the basal stem cells and migrate up to the surface
What are the four layers from the epidermis, from bottom up?
Stratum basale, Stratum spinosum, Stratum granulosum, Stratum corneum
Langerhans cells
Antigen presenting cells in the epidermis
Dermis
Connective tissue and blood vessels underneath the epidermis
Hair follices
Invaginated holocrine glands of the dermis (the epidermis invaginates); dermal papillae invaginates the fair follice bulb
Pilosebaceous unit
Consists of hair follice, Sebaceous gland, errcrine sweat gland, apocrine sweat gland, and arrector pili muscles
Meissner’s corpuscles
A dermal nerve ending used for fine touch
Pacinian corpuscles
A dermal/hypodermal junction nerve ending used for vibration, pressure, and temperature
Synovial joints
Joints lined by synovial membrane and filled with synovial fluid; articulating surfaces lined by hyaline cartilage over subchondral bone
Sharpey’s fibers
The fibers that connect tendons to bones
What are the three types of nonsynovial joints?
Symphyses, Synchondroses, Sutures
Tide Mark
The boundary between calcified and uncalcified cartilage in the articulate cartilage; prohibits ossification of cartilage layer
Synovium
Synovial joint lining with an inner layer and outer layer
Synovium inner layer
Discontinuous, 1-4 cells deep with no basement membrane. It’s a specialized connective tissue and not considered part of epithelium
Synovium outer layer
collagenous CT with blood vessels
Synoviocytes
Cells that linethe synovium; come in type A and type B
Type A synoviocyte
Macrophage-like, derived from mononuclear phagocyte lineage; can phagocytose debris in synovial fluid
Type B synoviocyte
Fibroblast-like; secrete hyaluronan (GAG) component of synovia and ECM fluid of synovium
Synovial fluid
Secreted by synoviocytes to fill the synovial cavity; functions to lubricate and nourish the joint
Osteoarthritis
Degeneration and disordered repair of articular cartilage that results in loss of bone at joints; causes cysts of synovial fluid in subchondral bone, sclerosis (thickened subchondral bone), Eburnation (polishing), and fibrillation (clefting)
Rheumatoid arthritis
An inflammatory autoimmune disorder that attacks joints, producing a nonsuppurative proliferative and inflammatory synovitis
Tendons
Connect mucles to bones; made of dense regular connective tissue
Ligaments
Connect bones to bones
Joint Capsules
Connect bones to bones
Symphyseal joints
Hyaline cartilage on bone surface connected by fibrocartilage with no joint cavity. Example: intervertebral disks
Nucleus pulposus
Fibrous and fliud filled, derived from notochord and found in intervertebral disk joints
Symphysis
Hyaline cartilage on bone surface connected by fibrocartilage
Synarthroses
Between cranial bones; Collagen fibers run from bone to bone