Pain Flashcards

1
Q

How much more common is depression for those with persistent pain?

A

4x more common

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What % of people with chronic pain will have another significant medical problem (i.e.: a co-morbidity)?

A

87%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is pain?

A

an unpleasant sensory and emotional experience associated with actual or potential tissue damage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Noxious

A

poisonous or harmful

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hyperalgesia

A

heightened pain intensity as a response to noxious stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Analgesia

A

absence of pain or inability to feel pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Dysaesthesia

A

abnormal sensation felt when touched, caused by damage to peripheral nerves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Paraesthesia

A

abnormal sensation with no apparent physical cause (e.g.: tingling, pricking, chilling, burning or numb sensation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Allodynia

A

innocuous (harmless) stimuli cause pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hyperpathia

A

exaggerated responses to painful stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the physiology of pain?

A
  1. An irritation or injury is detected in the peripheral nervous system by special nerves (nociceptors).
  2. A nerve impulse is then generated, sending a pain impulse towards the CNS.
  3. The message is received by the brain where the extent and significance of the irritation or injury is interpreted, and pain is sensed.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are nociceptors?

A

free nerve endings present in every tissue in the body except for the brain, which are activated by noxious stimuli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are examples of noxious stimuli?

A
  • Thermal: severe heat or cold
  • Mechanical: trauma, disease, injury, hypoxia, ulceration, infection, peripheral nerve damage, inflammation, ischaemia
  • Chemical: histamine, kinins, prostaglandins, which are released due to tissue damage and inflammation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 3-linked neurones that make up the ascending pathway of pain?

A
  • First-order neurons
  • Second-order neurons
  • Third-order neurons
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are first-order neurons?

A

travel from the nociceptors to the spine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are second-order neurons?

A

travel upwards through the spinal cord towards the thalamus in the brain

17
Q

What are third-order neurons?

A

run from the thalamus to the somatosensory area of the cerebral cortex

18
Q

How is line communication maintained?

A

by neurotransmitters (such as Substance P + Serotonin)

19
Q

What is the purpose of the descending pathway of pain?

A

to inhibit the sensation of pain

20
Q

How is pain sensation inhibited?

A

special neuropeptides with analgesic properties are released, which bind with opiate receptors, present throughout the CNS and block the action of neurotransmitter Substance P

21
Q

What are the 4 major categories of opiate receptor?

A
  • mu (πœ‡)
  • π‘˜π‘Žπ‘π‘π‘Ž
  • π‘ π‘–π‘”π‘šπ‘Ž
  • delta.
22
Q

What are the (3) ascending tracts of the spinal cord transmission pathway?

A
  • Spinothalamic
  • Spinoreticular
  • Dorsal column - medial lemniscal system
23
Q

What nerves are used to carry sensation from the head and oral cavity (trigeminal system)?

A
  • Trigeminal nerve
  • Facial nerve
  • Glossopharyngeal nerve
  • Vagus nerve
24
Q

What are the (3) classifications of pain duration?

A
  • Transient
  • Acute
  • Chronic
25
Q

What are the (3) classifications of pain type?

A
  • Nociceptive
  • Inflammatory
  • Neuropathic
26
Q

What is nociceptive pain?

A

detection of a noxious stimulus by nociceptors (C fibre)
- e.g.: mechanical, inflammatory, ischemic

27
Q

What is inflammatory pain?

A

pain signalling & transmission behaviour in the presence of an inflammatory process

28
Q

What is neuropathic pain?

A

a specific type of pain which results from damage to the signalling & transmission of neurons both within and outside of the CNS

29
Q

What is peripheral sensitisation?

A

caused by multiple chemical mediators from nerve tissue damage and inflammatory response

30
Q

What is central sensitisation?

A

change in the sensitivity of the spinal cord synapses in the dorsal horn and upstream through the nervous system to the cortex

31
Q

What are the (4) different sources of nociception?

A
  • Cutaneous (superficial somatic)
  • Deep somatic (bone, tendon + joint)
  • Visceral (internal organs)
  • Referred pain
32
Q

Describe transient pain characteristics?

A
  • Short duration
  • No significant consequence
  • Don’t seek medical attention
    e.g: stubbed toe or cut finger
33
Q

Describe acute pain characteristics?

A
  • Severe sudden onset, but is intense and can be intolerable
  • Could be associated to medical condition or injury
  • Brain response is to achieve homeostasis by initiating autonomic response
34
Q

Describe chronic (persistent) pain characteristics?

A
  • Continues even though healing is complete
  • No autonomic response
  • Considered a β€˜syndrome’ or medical condition in its own right
35
Q
A