Opioids

Question 0

Opioid with shortest half life

Answer 0

Remifentanil

Question 1

Opioid spectrum of use

Answer 1

Analgesic, antitussive, antidiarrheal

Question 2

Opioid with longest half life

Answer 2

Buprenorphine

Question 3

Mu opioid receptor function

Answer 3

Inhibition of respiration

Question 4

Mu opioid receptor affinity

Answer 4

Endorphins

Question 5

Delta opioid receptor function

Answer 5

Tolerance

Question 6

Delta opioid receptor affinity

Answer 6

Enkephalins

Question 7

Kappa opioid receptor function

Answer 7

Slowed GI transit

Question 8

Kappa opioid receptor affinity

Answer 8

Dynorphin

Question 9

Morphine effects

Answer 9

Miosis, Orthostatic hypotension, Respiratory depression, Pain relief, Histamine release, Increased ICP, Nausea, Euphoria

Question 10

Morphine MOA

Answer 10

Mu receptor agonist

Question 11

Fentanyl MOA

Answer 11

Mu receptor agonist

Question 12

Most potent opioid (18000x)

Answer 12

Ohmefentanyl

Question 13

Route of administration of Fentanyl

Answer 13

Transdermal or Lollipop

IV (anesthesia)

Question 14

Meperidine MOA

Answer 14

Mu and Kappa receptor agonist

Muscarinic blockade

Question 15

Pancreatitis pain relief DOC

Answer 15

Meperidine

Question 16

Opioid analgesic that does not cause miosis or biliary spasm

Answer 16

Meperidine

Question 17

Strong agonist at mu opioid receptors
Binds NMDA receptors
Glutamate antagonist

Answer 17

Methadone MOA

Question 18

Opioid for Opioid withdrawal/dependence

Answer 18

Methadone (Methadone Maintenance Therapy)

Question 19

Hydrocodone MOA

Answer 19

Mu and Kappa opioid receptor agonist

Question 20

Hydrocodone side effect

Answer 20

Hypogonadism and hearing loss

Question 21

Full opioid agonist

Answer 21

Morphine, Fentanyl, Meperidine, Methadone

Question 22

Partial opioid agonist

Answer 22

Hydrocodone, Dextromethorphan

Question 23

Dextromethorphan MOA

Answer 23

Sigma receptor stimulation depredd medullary cough center

Question 24

Dextromethorphan SimD

Answer 24

Codeine

Question 25

Codeine indication

Answer 25

Cough

Question 26

Weak opioid agonist

Answer 26

Propoxyphene

Question 27

Opioid agonist that cause fatal cardiotoxicity hence withdrawn

Answer 27

Propoxyphene

Question 28

Nalbuphine MOA

Answer 28

Kappa opioid receptor agonist | Mu opioid recetor ANTAgonist

Question 29

Mixed agonist-antagonist opioid

Answer 29

Nalbuphine

Question 30

Nalbuphine SimD

Answer 30

Buprenorphine, Butorphanol, Pentazocine

Question 31

Opioid resistant to naloxone reversal

Answer 31

Nalbuphine

Question 32

Opioid that decreases alcohol dependence

Answer 32

Buprenorphine

Question 33

Opioid antagonist

Answer 33

Naloxone

Question 34

Naloxone SimD

Answer 34

Naltrexone, Nalmefene

Question 35

Side effect of Naloxone in opioid dependent patients

Answer 35

Abstinence syndrome

Question 36

Tramadol MOA

Answer 36

Weak mu opioid receptor agonist | Inhibit uptake of NE and serotonin

Question 37

Side effect/contraindication of Tramadol

Answer 37

Seizures

Question 38

Tramadol SimD

Answer 38

Tapentadol

Question 39

Opioid overdose

Answer 39

Pupillary constriction, Coma, Respiratory Depression