Anti-Obesity Drugs Flashcards
1
Q
Orlistat MOA
A
Inhibits GI and Pancreatic Lipase
Reduce fat absorption
2
Q
Rebound weight gain upon discontinuation
A
Orlistat
3
Q
Orlistat contraindication
A
Pregnancy
4
Q
Side effect of Orlistat
A
Biliary stasis
Fat soluble vitamin malabsorption
Steatorrhea, Fecal Incontinence
5
Q
Sibutramine MOA
A
Inhibit NE and Serotonin reuptake
Reduce appetite
6
Q
Reason for Sibutramine withdrawal from market
A
Cardiovascular events and stroke
7
Q
Rimonabant MOA
A
Blocks Cannabinoid-1 receptor
Reduce appetite
8
Q
Reason for Rimonabant withdrawal form market
A
Rebound suicide and depression
9
Q
Adverse effect of Bangkok Pills
A
Valvular Heart Disease
10
Q
Bangkok Pills content
A
Fenfluramine, Ephedrine, Phentermine