Anti TB Drugs

Question 1

Bactericidal Anti-mycobacterial

Answer 1

HRZS

Question 2

Bacteriostatic Anti-mycobacterial

Answer 2

EZ

Question 3

Inhibits mycolic acid synthesis

Answer 3

Isoniazid

Question 4

Side effect of Isoniazid

Answer 4

Neurotoxic and Hepatotoxic

Question 5

Neurotoxicity prevention for isoniazid

Answer 5

Pyridoxine

Question 6

Rifamycin

Answer 6

Rifampicin, Rifabutine, Rifapentine

Question 7

RNA polymerase inhibitor

Answer 7

Rifampicin

Question 8

Red orange urine

Answer 8

Rifampicin

Question 9

Anti-mycobacterial that rapidly develop resistance if used alone

Answer 9

Rifampicin

Question 10

Indications of Rifampicin

Answer 10

TB, Leprosy
Drug resistant infections
Meningococcal, Staphylococcal

Question 11

Inhibits arabinosyl transferase involved in arabinogalactan synthesis in cell wall

Answer 11

Ethambutol

Question 12

Red-green color blindness

Answer 12

Ethambutol

Question 13

Retrobulbar neuritis

Answer 13

Ethambutol

Question 14

Bactericidal only on actively dividing mycobacteria

Answer 14

Pyrazinamide

Question 15

Most hepatotoxic Anti-TB drug

Answer 15

Pyrazinamide

Question 16

Sterilizing Anti-TB drug

Answer 16

Pyrazinamide

Question 17

Anti-TB drug causing asymptomatic hyperuricemia

Answer 17

Pyrazinamide

Question 18

Hepatotoxic anti-TB drugs

Answer 18

Isoniazid < Rifampicin < Pyrazinamide

Question 19

Antimycobacterial Aminoglycoside

Answer 19

Streptomycin

Question 20

Streptomycin-resistant or MDR-TB

Answer 20

Amikacin

Question 21

First-line-drug-resistant TB

Answer 21

Ciprofloxacin, Ofloxacin

Question 22

Bacteriostatic anti-leprosy drug

Answer 22

Dapsone, Acedapsone

Question 23

Bactericidal anti-leprosy drug

Answer 23

Clofazimine

Question 24

Anti-mycobacterial drug inhibiting folic acid synthesis

Answer 24

Dapsone

Question 25

Side effect of Dapsone

Answer 25

Methemoglobinemia

Question 26

Most active drug against Mycobacterium leprae

Answer 26

Dapsone

Question 27

Lepromatous Leprosy DOC

Answer 27

Dapsone + Cofazimine + Rifampicin

Question 28

Tuberculous Leprosy DOC

Answer 28

Dapsone + Rifampicin

Question 29

Anti-leprosy drug causing skin discoloration

Answer 29

Clofazimine

Question 30

Clofazimine MOA

Answer 30

Binds to guanine bases in bacterial DNA

Question 31

Mycobacterium avium prophylaxis CD4 < 50

Answer 31

Clarithromycin or Azithromycin

with or without Rifabutin

Question 32

Treatment of Atypical Mycobacterial infection

Answer 32

Azithromycin or Clarithromycin plus

Rifabutin AND Ethambutol