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Pharmacology > Anterior Pituitary > Flashcards

Anterior Pituitary Flashcards

1
Q

Growth Hormone agonist

A

Somatropin

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2
Q

Banned performance-enhancing drug in athletes

A

Somatropin

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3
Q

Octreotide MOA

A

Suppresses GH, IGF-1, serotonin and GI peptides

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4
Q

GH antagonist

A

Octreotide

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5
Q

Order of Ovulation Induction Protocol

A

GnRH agonist or antagonist to inhibit endogenous gonadotropin production - FSH to promote follicle development - LH or hCG for oocyte maturation

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6
Q

Most common side effect of ovulation induction

A

Ovarian hyperstimulation syndrome

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7
Q

Ovarian hyperstimulation syndrome manifestations

A

ovarian enlargement, ascites, hypovolemia and shock

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8
Q

FSH analog

A

Follitropin

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9
Q

T/F: Multiple pregnancy is a side effect of ovarian hyperstimulation

A

True

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10
Q

Use of gonadotropin analogs in males

A

infertility

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11
Q

Use of gonadotropin analogs in females

A

ovulation

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12
Q

LH analog

A

Choriogonadotropin

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13
Q

Hypogonadotropic hypogonadism DOC

A

LH analog

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14
Q

GnRH analog

A

Leuprolide, Gonadorelin (-relin)

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15
Q

GnRH intermittent administration

A

increase LH and FSH

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16
Q

GnRH continuous administration

A

decrease LH and FSH

17
Q

Precocious puberty

A

Leuprolide

18
Q

Prostate cancer

A

Leuprolide

19
Q

Used with leuprolide to avoid exacerbation of precocious puberty or prostate cancer

A

Flutamide

20
Q

GnRH antagonist

A

Ganirelix (-relix)

21
Q

T/F: Ganirelix causes tumor-flare in prostate cancer treatment

A

FALSE

22
Q

Hyperprolactinemia DOC

A

Bromocriptine

23
Q

Milk let down

A

Oxytocin

24
Q

Metabolic side effect of oxytocin

A

fluid retention/water intoxication

25
Q

ADH agonist

A

Desmopressin

26
Q

ADH antagonist

A

Conivaptan (-vaptan)

27
Q

Central Diabetes Insipidus DOC

A

Desmopressin

28
Q

Polyuria, Poldyipsia, Hypernatremia

A

Diabetes Insipidus

29
Q

Polyuria, Polydipsia, Weight Loss

A

Diabetes Mellitus

30
Q

Deficient ADH

A

Central Diabetes Insipidus

31
Q

End-organ resistance to ADH

A

Nephrogenic Diabetes Insipidus

32
Q

Receptors antagonized by Conivaptan

A

V1 and V2

33
Q

Rapid correction of hyponatremia results in

A

Central Pontine Myelinolysis

34
Q

SIADH DOC

A

Conivaptan (-vaptan)

Pharmacology (31 decks)

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