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Pharmacology > Anti-Seizure > Flashcards

Anti-Seizure Flashcards

0
Q

Complex partial seizure / Simple partial seizure:

Intact consciousness

A

Simple partial seizure

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1
Q

Complex partial seizure / Simple partial seizure:

Loss of consciousness

A

Complex partial seizure

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2
Q

Phenytoin MOA

A

Na channel blocked

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3
Q

Carbamazepine MOA

A

Na channel blocked

Glutamate decrease

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4
Q

Valproic Acid MOA

A

Na channel blocked
Ca channel blocked
GABA decrease
NMDA blocked

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5
Q

Class of Phenytoin

A

Hydantoin

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6
Q

Teratogenic effect of phenytoin

A

Fetal hydantoin syndrome

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7
Q

Phenobarbital MOA

A

Na channel blocked
Glutamate decrease
GABA decrease

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8
Q

Class of carbamazepine

A

TCA

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9
Q

Teratogenic effect of Valproic acid

A

Spina bifida

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10
Q

Antiseizure drug for children and pregnant

A

Phenobarbital

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11
Q

Absence seizures DOC

A

Ethosuxamide

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12
Q

Ethosuxamide MOA

A

Ca channel blocked (t-type, thalamus)

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13
Q

Status Epilepticus DOC with no co-morbids

A

Diazepam

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14
Q

Clonazepam MOA

A

GABA decrease

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15
Q

Gabapentin MOA

A

Ca channel blocked
GABA decrease
Glutamate decrease

16
Q

Lamotrigine MOA

A

Na channel blocked
Ca channel blocked
Glutamate channel blocked

17
Q

Anti-seizure that cause Steven-Johnson syndrome

A

Lamotrigine

18
Q

Ethosuxamide class

A

Cyclic ureide

19
Q

Gabapentin class

A

GABA derivative

20
Q

Lamotrigine class

A

Phenyltriazine

21
Q

Levetiracetam class

22
Q

Levetiracetam MOA

A

Ca channel blocked
GABA decrease
Glutamate decrease
Binds synaptic vesicular protein SV2A

23
Q

Juvenile myocolonic epilepsy

A

Levetiracetam

24
Q

Contraindication in Levetiracetam

A

Schizophrenia

25
Q

Topiramate class

A

Monosaccharide derivative

26
Q

Topiramate MOA

A 
Na channel blocked
Ca channel blocked
GABA decrease
Glutamate decrease
Carbonic Anhydrase decrease
27
Q

Anti-seizure with side effect of Lennox-Gastaut syndrome & West syndrome

A

Topiramate

28
Q

Anti-seizure with most number of MOA

A

Topiramate

29
Q

Bipolar Disorder (mania) DOC

A

Valproic Acid

30
Q

Trigeminal Neuralgia DOC

A

Carbamazepine

31
Q

Neuropathic pain DOC

A

Gabapentin

Pregabalin

32
Q

Migraine DOC

A

Gabapentin
Phenytoin
Topiramate

33
Q

Myoclonic and Atypical Absence DOC

A

Valproic Acid

34
Q

Generalized Tonic-Clonic Seizure DOC

A

Phenytoin
Valproic acid
Carbamazepine

35
Q

Partial seizure DOC

A

Phenytoin
Lamotrigine
Carbamazepine

36
Q

Status Epilepticus DOC in hepatic failure

Pharmacology (31 decks)

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