Anti-Seizure

Question 0

Complex partial seizure / Simple partial seizure:

Intact consciousness

Answer 0

Simple partial seizure

Question 1

Complex partial seizure / Simple partial seizure:

Loss of consciousness

Answer 1

Complex partial seizure

Question 2

Phenytoin MOA

Answer 2

Na channel blocked

Question 3

Carbamazepine MOA

Answer 3

Na channel blocked

Glutamate decrease

Question 4

Valproic Acid MOA

Answer 4

Na channel blocked
Ca channel blocked
GABA decrease
NMDA blocked

Question 5

Class of Phenytoin

Answer 5

Hydantoin

Question 6

Teratogenic effect of phenytoin

Answer 6

Fetal hydantoin syndrome

Question 7

Phenobarbital MOA

Answer 7

Na channel blocked
Glutamate decrease
GABA decrease

Question 8

Class of carbamazepine

Answer 8

TCA

Question 9

Teratogenic effect of Valproic acid

Answer 9

Spina bifida

Question 10

Antiseizure drug for children and pregnant

Answer 10

Phenobarbital

Question 11

Absence seizures DOC

Answer 11

Ethosuxamide

Question 12

Ethosuxamide MOA

Answer 12

Ca channel blocked (t-type, thalamus)

Question 13

Status Epilepticus DOC with no co-morbids

Answer 13

Diazepam

Question 14

Clonazepam MOA

Answer 14

GABA decrease

Question 15

Gabapentin MOA

Answer 15

Ca channel blocked
GABA decrease
Glutamate decrease

Question 16

Lamotrigine MOA

Answer 16

Na channel blocked
Ca channel blocked
Glutamate channel blocked

Question 17

Anti-seizure that cause Steven-Johnson syndrome

Answer 17

Lamotrigine

Question 18

Ethosuxamide class

Answer 18

Cyclic ureide

Question 19

Gabapentin class

Answer 19

GABA derivative

Question 20

Lamotrigine class

Answer 20

Phenyltriazine

Question 21

Levetiracetam class

Answer 21

Piracetam

Question 22

Levetiracetam MOA

Answer 22

Ca channel blocked
GABA decrease
Glutamate decrease
Binds synaptic vesicular protein SV2A

Question 23

Juvenile myocolonic epilepsy

Answer 23

Levetiracetam

Question 24

Contraindication in Levetiracetam

Answer 24

Schizophrenia

Question 25

Topiramate class

Answer 25

Monosaccharide derivative

Question 26

Topiramate MOA

Answer 26

``` Na channel blocked Ca channel blocked GABA decrease Glutamate decrease Carbonic Anhydrase decrease ```

Question 27

Anti-seizure with side effect of Lennox-Gastaut syndrome & West syndrome

Answer 27

Topiramate

Question 28

Anti-seizure with most number of MOA

Answer 28

Topiramate

Question 29

Bipolar Disorder (mania) DOC

Answer 29

Valproic Acid

Question 30

Trigeminal Neuralgia DOC

Answer 30

Carbamazepine

Question 31

Neuropathic pain DOC

Answer 31

Gabapentin | Pregabalin

Question 32

Migraine DOC

Answer 32

Gabapentin Phenytoin Topiramate

Question 33

Myoclonic and Atypical Absence DOC

Answer 33

Valproic Acid

Question 34

Generalized Tonic-Clonic Seizure DOC

Answer 34

Phenytoin Valproic acid Carbamazepine

Question 35

Partial seizure DOC

Answer 35

Phenytoin Lamotrigine Carbamazepine

Question 36

Status Epilepticus DOC in hepatic failure

Answer 36

Lorazepam