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Pharmacology > Anti-infectives > Flashcards

Anti-infectives Flashcards

0
Q

Act on bowel lumen

A

Luminal amebicide

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1
Q

Act on bowel wall and liver

A

Tissue amebicide

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2
Q

Luminal amebicides

A

Diloxanide Furoate, Iodoquinol, Paramomycin

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3
Q

Tissue amebicide

A

Emetine, Metronidazole, Nitazoxanide

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4
Q

Asymptomatic E. histolytica cyst DOC

A

Diloxanide furoate

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5
Q

Mild to moderate intestinal infection DOC

A

Metronidazole + Luminal amebicide

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6
Q

Severe and Extraintestinal infection, Hepatic abscess DOC

A

Metronidazole/Imidazole + Luminal amebicide

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7
Q

Severe intestinal and extraintestinal amebiasis back up drug for Metronidazole

A

Emetine

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8
Q

Antiprotozoal that causes thyroid enlargement

A

Iodoquinol

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9
Q

Antiprotozoal that blocks ribosomal movement along mRNA

A

Emetine

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10
Q

Metallic tasting antiprotozoal

A

Metronidazole

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11
Q

Paramomycin MOA

A

Binds to 16s ribosomal subunit inhibiting protein synthesis

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12
Q

Cryptosporidiosis drug of choice

A

Nitazoxanide

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13
Q

Metronidazole-resistant amebiasis

A

Nitazoxanide

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14
Q

Pneumocystosis DOC for treatment and prophylaxis

A

Cotrimoxazole

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15
Q

Toxoplasmosis DOC for treatment and prophylaxis

A

Pyrimenthamine-Sulfadiazine

16
Q

Cerebral toxoplasmosis on CT

A

Ring like opacities

17
Q

Advanced East African sleeping sickness DOC

A

Suramine + Melarsoprol

18
Q

Advanced West African sleeping sickness DOC

A

Pentamidine + Enflornithine

19
Q

Anti-trypanosomal drug crossing the blood brain barrier

A

Melarsoprol and Enflornithine

20
Q

Hemolymphatic stage, East african sleeping sickness DOC

A

Suramin

21
Q

Hemolymphatic stage, West african sleeping sickness DOC

A

Pentamidine

22
Q

Chagas disease DOC

A

Nifurtimox

23
Q

Melarsoprol route of administration

A

Intramuscular

24
Q

Leishmaniasis DOC (except India)

A

Sodium Stibogluconate

25
Q

Leishmaniasis DOC in India

A

Amohotericin B / Miltefosine

Pharmacology (31 decks)

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