Gastrointestinal drugs Flashcards
Magnesium OH side effect
Diarrhea
Milk-Alkali syndrome
Magnesium-Aluminum Hydroxide
Aluminum OH side effect
Constipation
Supresses nocturnal scid secretion more than meal-stimulated secretion
H2 blocker
Blockade of H/K ATPase in active gastric parietal cells
Proton Pump Inhibitor
Long-lasting effect on both nocturnal acid secretion and meal stimulated secretion
Proton Pump Inhibitor
Prevention of NSAID induced gastric mucosal injury
Misoprostol
Mucosal protective agent causing blackening of tongue and stools
Bismuth Salicylate
Forms protective covering over ulcer beds
Sucralfate
Blocks D2 receptors and act as antiemetic
Metoclopramide and Domperidone
Diabetic gastroparesis DOC
Domperidone, Metoclopramide
T/F: Metoclopramide crosses the blood brain barrier
True
Erythromycin act as prokinetic agent by stimulating which receptors causing increased gastric emptying and intestinal motility
Motilin receptors
Bulk forming
Psyllium
Stool softening
Docusate
Osmotic laxative
Lactulose
Stimulant or Cathartic laxative
Bisacodyl
Melanosis coli
Senna
Anthraquinone-containing laxative
Senna
Accumulation of brown lipofuscin in macrophages of the colon
Melanosis coli
Castor oil
Cathartic / Stimulant
Glycerine suppository
Stool softener
Methylcellulose
Bulk forming
Mineral oil
Stool softener
Polycarbophil
Bulk forming
Cascara
Stimulant / Cathartic
Diphenoxylate
Loperamide, Colloidal Bismuth, Kaolin Pectin
Activates opioid receptors in the enteric nervous system
Diphenoxylate
Side effect of loperamide given in children < 4 years
Paralytic ileus
Drug to reverse ileus
Bethanecol
5 HT3 receptor antagonist
Ondansetron
Immunomodulator for inflammatory bowel disease
Mesalamine
