Gastrointestinal drugs Flashcards

0
Q

Magnesium OH side effect

A

Diarrhea

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1
Q

Milk-Alkali syndrome

A

Magnesium-Aluminum Hydroxide

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2
Q

Aluminum OH side effect

A

Constipation

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3
Q

Supresses nocturnal scid secretion more than meal-stimulated secretion

A

H2 blocker

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4
Q

Blockade of H/K ATPase in active gastric parietal cells

A

Proton Pump Inhibitor

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5
Q

Long-lasting effect on both nocturnal acid secretion and meal stimulated secretion

A

Proton Pump Inhibitor

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6
Q

Prevention of NSAID induced gastric mucosal injury

A

Misoprostol

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7
Q

Mucosal protective agent causing blackening of tongue and stools

A

Bismuth Salicylate

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8
Q

Forms protective covering over ulcer beds

A

Sucralfate

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9
Q

Blocks D2 receptors and act as antiemetic

A

Metoclopramide and Domperidone

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10
Q

Diabetic gastroparesis DOC

A

Domperidone, Metoclopramide

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11
Q

T/F: Metoclopramide crosses the blood brain barrier

A

True

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12
Q

Erythromycin act as prokinetic agent by stimulating which receptors causing increased gastric emptying and intestinal motility

A

Motilin receptors

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13
Q

Bulk forming

A

Psyllium

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14
Q

Stool softening

A

Docusate

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15
Q

Osmotic laxative

16
Q

Stimulant or Cathartic laxative

17
Q

Melanosis coli

18
Q

Anthraquinone-containing laxative

19
Q

Accumulation of brown lipofuscin in macrophages of the colon

A

Melanosis coli

20
Q

Castor oil

A

Cathartic / Stimulant

21
Q

Glycerine suppository

A

Stool softener

22
Q

Methylcellulose

A

Bulk forming

23
Q

Mineral oil

A

Stool softener

24
Polycarbophil
Bulk forming
25
Cascara
Stimulant / Cathartic
26
Diphenoxylate
Loperamide, Colloidal Bismuth, Kaolin Pectin
27
Activates opioid receptors in the enteric nervous system
Diphenoxylate
28
Side effect of loperamide given in children < 4 years
Paralytic ileus
29
Drug to reverse ileus
Bethanecol
30
5 HT3 receptor antagonist
Ondansetron
31
Immunomodulator for inflammatory bowel disease
Mesalamine