Anti-Malarial Drugs Flashcards
Kills schizonts in erythrocytes
Blood schizonticide
Kills liver schizonts or hypnozoites
Tissue schizonticide
Kills gametes in human blood
Gametocide
Prevent sporogony and multiplication in vector
Sporonticide
Dormant liver hypnozoites
P. vivax, P. ovale
Pigment of malaria
Hemozoin
Chloroquine MOA
Prevents polymerization of heme to hemozoin
Blood schizonticide
Chloroquine, Quinine, Mefloquine, Doxycycline, Lumefantrine, Artemisinin
Blood and Tissue schizonticide
Primaquine, Atovaquone
Non-falciparum chloroquine-sensitive malaria DOC
Chloroquine
Non-falciparum chloroquine-sensitive malaria prophylaxis
Chloroquine
chloroquine-resistant malaria DOC
Quinidine
chloroquine-resistant malaria prophylaxis
Mefloquine
Malaria DOC in pregnant
Quinidine
Severe falciparum Malaria DOC
Quinidine