Drugs of Abuse Flashcards
It is a state characterised by experiencing opposite drug effects upon drug withdrawal
Drug dependence
Use of illicit drug for a nonmedical purpose despite knowing its harmful effects. Motivated by anticipated pleasure.
Drug abuse
It is the compulsive use of illicit drug for personal satisfaction in the face of known health risk
Drug addiction
State of decreased response to a drug necessitating larger doses for drug to take effect.
Drug tolerance
Etiologies of tolerance:
Increased disposition of drug
Metabolic tolerance
Etiologies of tolerance:
Ability to compensate for the effects of the drug
Behavioral tolerance
Etiologies of tolerance:
Changes in receptor or effector systems involved in drug action
Functional tolerance
Signs and symptoms that occur during drug withdrawal in a drug dependent person
Abstinence or Withdrawal syndrome
Excessive stimulation of which neurotransmitted cause pathologic reinforcement as in drug abuse
Dopamine
Common features of addiction
Uncontrollable compulsive behavior
Side effect of chronic high dose amphetamine abuse
Necrotizing arteritis
MDMA street name
Ecstasy
MDMA MOA
SSRI
Cocaine MOA
Dopamine, NE and Serotonin inhibitor
Pulmonary finding in cocaine
Hemorrhagic alveolitis
