Oesophageal and Gastric Pathology

Question 1

What are the consequences of chronic GORD to the oesophageal epithelium. What can cause the same process in the stomach? The gallbladder?

Answer 1

• Oesophagitis, Barrett’s, adenocarcinoma
• H. pylori
• Gallstones

Question 2

What is eosinophilic oesophagitis? Where in the oesophagus does it mostly occur?

Answer 2

• Atopy-related eosinophilic inflammation of the proximal oesophagus (as opposed to GORD, which is more distal)

Question 3

Where are SCC and adenocarcinomas most likely to be in the oesophagus?

Answer 3

• SCC - middle third (smoking related)
• Adenocarcinoma - lower third (Barrett’s related)

Question 4

Where do H. pylori infections mostly occur?

Answer 4

Antrum of stomach

Question 5

What can chronic H. pylori infection in the stomach lead to?

Answer 5

• Lymphoma (MALToma)