Hepatocellular Carcinoma Flashcards
1
Q
What are the risk factors for the development of hepatocellular carcinoma?
A
- Cirrhosis
- Chronic HBV/HCV infection
- Chronic alcohol use
- Diabetes
- Obesity
- FHx
2
Q
What might be a good investigative trail in a patient suspected of having hepatocellular carcinoma?
A
- FBC (thrombocytopaenia)
- LFTs (including albumin, coags)
- Hepatitis screening
- aFP levels (raised in HCC)
- Ultrasound
3
Q
How is hepatocellular carcinoma generally managed?
A
- Resection
- Sorafenib
- Liver transplant
4
Q
What are the general history/examination signs in a person with a liver tumour?
A
- Fever
- Malaise
- Anorexia
- Weight loss
- RUQ pain
- Jaundice (late except cholangiocarcinoma)
- Signs of chronic liver disease if HCC
5
Q
What cancerous organs are most likely to seed metastases into the liver?
A
Stomach, lung, colon, breast, uterus
