Liver Pathology Flashcards
1
Q
What is the main histological difference between acute and chronic viral hepatitis infection?
A
- Lobular (acute) vs. periportal (chronic) inflammation
2
Q
How are NAFLD and AFLD distinguished?
A
- On history. NAFLD is a hepatic manifestation of the metabolic syndrome and AFLD a manifestation of alcoholic disease.
- Both exhibit similar histology
3
Q
Must HCC development progress through the development of cirrhosis?
A
No (especially not with HCV infection)
4
Q
Hepatic adenomas are a benign liver tumour but can sometimes present acutely. How?
Which population are they most common in?
A
- RUQ and intraperitoneal bleeding
- Young women on the OCP
5
Q
What serum marker might you use to track HCC development?
A
aFP
6
Q
Who normally develops primary biliary sclerosis? How is it diagnosed? How is it treated?
A
- Middle aged females - loss of small bile ducts
- AMA levels
- Ursodeoxycholic acid
