Cardiometabolic Syndrome

Question 1

Give a set of diagnostic criteria for the metabolic syndrome

Answer 1

• Abdominal obesity
  
  • 94M, 80F in Europeans
  • 90M, 80F in South Asian/Chinese)
• AND 2 or more of
  
  • Elevated triglycerides (> 1.7 mmol/L)
  • Low HDL-C (< 0.9 mmol/L M, < 1.3 mmol/L F)
  • High BP (130/85 or treated)
  • Hyperglycaemia (FPG > 5.6 mmol/L or diagnosed T2D)

Question 2

What are the main complication risks for patients with the metabolic syndrome?

Answer 2

3 x risk of stroke of heart attack

5 x more likely to develop T2D

Question 3

Outline the management prinicples for patients with the metabolic syndrome

Answer 3

• Address glucose intolerance and prevent diabetes
  
  • Lifestyle interventions (diet and exercise)
  • Pharmacological anti-hyperglycaemics
  • Lap-banding
• Reduce CV risk
  
  • Lifestyle interventions
  • Statins
  • ACEIs