Diffuse Lung Disease Flashcards
What does the label “diffuse lung disease” actually refer to?
- Cough
- Dyspnoea
- X-ray showing diffuse lung involvement
What are acute pathological processes that could cause an diffuse lung pattern on x-ray?
- Water - e.g. APO
- Inflammation - inhalation injury, acute drug toxicity, acute infection
- Blood - diffuse leakage e.g. vasculitis
What diseases might cause a sub-acute or chronic diffuse lung disease picture on xray? Specifically, list some drugs.
- Idiopathic pulmonary fibrosis
- Sarcoidosis
- Occupational (asbestosis)
- Extrinsic allergic (bird-fancier’s/farmer’s lung)
- Drugs (methotrexate, amiodarone, bleomycin, cyclophosphamide)
- Radiotherapy
- Connective tissue disease (RA, SLE etc.)
- Vasculitis
List some signs you might expect to find on examination in a patient with diffuse lung disease
- Crackles
- Clubbing
- Connective tissue disorders
- Pulmonary hypertension signs
How might you assess pulmonary hypertension non-invasively?
Echocardiogram (TR/PR)
What general diseases could result in a reticular/honeycombing, basal, diffuse lung picture on xray?
- IPF
- Connective tissue diseases
- Asbestosis
What diffuse lung diseases tend to cause an upper lobe nodular pattern on xray?
Silicosis, sarcoidosis
What xray pattern do drugs causing lung disease ted to create?
Any.