Neuroscience Week 5: Autonomic Nervous System: Parasympathetic Functional Anatomy

Question 1

Organ systems parasympathetic response

Answer 1

Question 2

Oculomotor parasympathetic actions & associated ganglia

Answer 2

Question 3

autonomic regulation of pupil diameter

Answer 3

Question 4

Circular fibers of the eye

Answer 4

• parasympathetic control
• smooth muscle
• constricts iris
• sphincter pupillae

Question 5

Radial Fibers of eye

Answer 5

• sympathetic control
• dilator pupillae
• smooth muscle
• dilates iris

Question 6

Parasympathetics of Facial nerve

Answer 6

• lacrimal gland tear production
• submandiubular salivary gland
• sublingual salivary secretion

Through the pterygopalatine ganglion and submandibular ganglion

Question 7

Parasympathetics of glossopharyngeal nerve and associated ganglia

Answer 7

• otic ganglion
• Parotid gland
• glands of the posterior tongue

Question 8

Parasympathetic ganglion of facial nerve

2 listed

Answer 8

Pterygopalatine ganglion

and

submandibular ganglion

Question 9

Parasympathetic ganglion of glossopharyngeal nerve

Answer 9

Otic ganglion

Question 10

Parasympathetic ganglion of Vagus nerve

5 listed target tissues

Answer 10

to stomach

to heart

to intestines

to lungs

to liver

*SHILL*

Question 11

Basic functional structure of parasympathetics

Answer 11

• cranio-sacral origins
• long preganglionics
• very short postganglionics

Question 12

Sacral parasympathetic innervation origin and targets

Answer 12

• comes out of cauda equina
• Left colic flexure of large intestines
• Bladder
• Penis
• Clitoris

Question 13

Question 1

Answer 13

C

Difficulty with completely voiding during a trip to the bathroom

Question 14

Sacral parasympathetic innervation outflow

Answer 14

Question 15

The left colic flexure separates what?

Answer 15

cranial parasympathetic innervation from sacral splanchnic innervation

Question 16

vagal stimulation of the heart

Answer 16

Question 17

Otto Loewi’s Experiment

Answer 17

Question 18

neurotransmitters of parasympathetic post ganglionics

Answer 18

Question 19

Acetylcholine in parasympathetics

Answer 19

Question 20

Parasympathetic nervous system

Answer 20

Question 21

How do muscarinic ACh receptors transduce their signal?

Answer 21

work through second messengers

Question 22

Muscarinic Receptor subtypes

Answer 22

• M1
• M2
• M3
• M4
• M5

Question 23

Phospholipase C system

Answer 23

gets calcium to increase inside cells

Question 24

Acetylcholine Receptors Slow-sustained type

Answer 24

Muscarinic metabotropic

Question 25

Acetylcholine receptor fast short-lived type

Answer 25

Nicotinic ionotropic

Question 26

M3 receptors function and location

Answer 26

Smooth muscle

Question 27

M2 Receptor

Answer 27

* Gi coupled * inhibits adenylate cyclase * cardiac inhibition

Question 28

Parasympathetic receptor on the bladder

Answer 28

M3 on the fundus and external sphincter

Question 29

Muscarinic Receptor subtypes overview

Answer 29

Question 30

M1 Second Messenger

Answer 30

* Stimulation of Phospholipase C

Question 31

M1 Targets

Answer 31

* CNS * Enteric Nervous System

Question 32

M1 Effects

Answer 32

* Undefined * Gastric Acid Secretion

Question 33

M2 Second Messenger

Answer 33

* Inhibition of Adenylate Cyclase * Activation of K⁺ channels

Question 34

M2 Targets

Answer 34

Heart

Question 35

M2 Effects

Answer 35

Inhibition

Question 36

M3 Second Messenger

Answer 36

* Stimulation of Phospholipase C

Question 37

M3 Targets

Answer 37

* Smooth muscle * Secretory Glands

Question 38

M3 Effects

Answer 38

* Contraction * Secretion

Question 39

M4 Second Messenger

Answer 39

Inhibition of Adenylate Cyclase

Question 40

M4 targets

Answer 40

?

Question 41

M4 Effects

Answer 41

?

Question 42

M5 Second Messenger

Answer 42

Stimulation of Phospholipase C

Question 43

M5 Targets

Answer 43

CNS

Question 44

M5 Effects

Answer 44

Undefined

Question 45

Parasympathetic summary

Answer 45

Question 46

Parasympathetic preganglionic origins which nerves?

Answer 46

* Craniosacral origins * Cranial nerves VII, III, IX and X * Cauda equina sacral origins * S2-S4